Results 281 to 290 of about 48,697 (308)
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[8] Lysophosphatidylcholine acyltransferase
1992Publisher Summary This chapter discusses lysophosphatidylcholine acyltransferase. Lyso-PC:acyl-CoA acyltransferase activity is detected in various mammalian tissues, bacteria, protozoa, and plants. The transfer of acyl groups from acyl-CoA to 1-acylglycerophosphocholine (1-acyl-GPC) is catalyzed by 1-acyl-GPC: acyl-CoA acyltransferase, whereas ...
Patrick C. Paul +2 more
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A protein cofactor of lecithin:Cholesterol acyltransferase
Biochemical and Biophysical Research Communications, 1972Abstract The effect of proteins isolated from human high density lipoprotein on cholesterol esterification by purified lecithin:cholesterol acyltransferase in the presence of dispersed lipids was studied. One of the major proteins present gave a maximal rate of esterification similar to that found with the native lipoprotein.
V.G. Shore +5 more
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Purification and Characterization of Lecithin:Cholesterol Acyltransferase
Scandinavian Journal of Clinical and Laboratory Investigation, 1978The purification of lecithin:cholesterol acyltransferase (LCAT] from human plasma is reported. Hydroxylapatite fractions were approximately 16,000 fold purified over the starting plasma and were free of high-density lipoprotein (HDL) and albumin.
K G Varma, E Gustow, L A Soloff
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A review on lecithin:cholesterol acyltransferase deficiency
Clinical Biochemistry, 2015Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme which esterifies cholesterol, and plays a key role in the metabolism of high-density lipoprotein cholesterol (HDL-C). Genetic disorders of LCAT are associated with lipoprotein abnormalities including low levels of HDL-C and presence of lipoprotein X, and clinical features mainly corneal ...
Min Li, Ramesh Saeedi, Jiri Frohlich
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Mammalian acyl-CoA:cholesterol acyltransferases
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000Cholesterol, the chief sterol found in vertebrates, exists both as a free sterol and as a component of cholesterol esters, which are synthesized by acyl-CoA:cholesterol acyltransferase (ACAT) enzymes. Considerable knowledge concerning cholesterol ester metabolism has accumulated during the past century. However, rapid advances have occurred in the past
Michel Accad +2 more
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Lecithin:retinol acyltransferase in ARPE-19
Experimental Eye Research, 2005The purpose of this study is to investigate if a readily available cell line (APRE-19) may be used to study in vitro function of visual cycle enzymes such as lecithin:retinol acyltransferase (LRAT). Cells incubated with exogenous retinol accumulated intracellular all-trans retinol and all-trans retinyl ester.
Steven T. Schuschereba +3 more
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Molecular recognition in carnitine acyltransferases
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 1989We are designing and synthesizing rigid guests to probe the topography of the carnitine acyltransferases, regulatory enzymes in lipid metabolism. Our designs are based on structural studies of substrates and possible molecular mechanisms of enzymatic activity. Recent X-ray, 1H NMR, and force-field computational studies on carnitine and acetylcarnitine,
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Microsomal carnitine acyltransferases
Biochemical Society Transactions, 1995E D Saggerson, N. M. Broadway
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Characterization and properties of carnitine acyltransferases [PDF]
Biochemical Society Transactions, 1986 Loran L. Bieber, Carol J. Fiol
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