Results 261 to 270 of about 58,776 (313)
Some of the next articles are maybe not open access.
Physiological Functions of Phospholipid:Diacylglycerol Acyltransferases
Plant And Cell Physiology, 2023Abstract Triacylglycerol (TAG) is among the most energy dense storage forms of reduced carbon in living systems. TAG metabolism plays critical roles in cellular energy balance, lipid homeostasis, cell growth and stress responses. In higher plants, microalgae and fungi, TAG is assembled by acyl-CoA-dependent and acyl-CoA-independent ...
Saroj Kumar Sah +4 more
openaire +2 more sources
Dihydroxyacetone phosphate acyltransferase
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1997In this article the properties, assay, distribution, subcellular localization, deficiency in congenital peroxisomal disorders, purification and physiological functions of dihydroxyacetone phosphate acyltransferase (EC 2.3.1.42) are reviewed.
openaire +2 more sources
ACYL-COENZYME A:CHOLESTEROL ACYLTRANSFERASE
Annual Review of Biochemistry, 1997Due to its presumed role in regulating cellular cholesterol homeostasis, and in various pathophysiological conditions, acyl-coenzyme A:cholesterol acyltransferase (ACAT) has attracted much attention. Cloning the ACAT gene provides the necessary tool to advance molecular studies of this enzyme.
T Y, Chang, C C, Chang, D, Cheng
openaire +2 more sources
Lecithin cholesterol acyltransferase
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000Cholesterol transport in circulation and its removal from tissues depends on the activity of lecithin cholesterol acyltransferase (LCAT). LCAT is a soluble enzyme that converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lyso-phosphatidylcholines on the surface of high-density lipoproteins.
openaire +2 more sources
Inhibitors of Acyl CoA:Cholesterol Acyltransferase
Journal of Medicinal Chemistry, 1996Conformational restriction of previously disclosed acyclic (diphenylethyl)diphenylacetamides led to the discovery of several potent inhibitors of acyl CoA:cholesterol acyltransferase (ACAT). cis-[2-(4-Hydroxyphenyl)-1-indanyl]diphenylacetamide (4a) was the most potent ACAT inhibitor identified (IC50 = 0.04 microM in an in vitro rat hepatic microsomal ...
W, Vaccaro +9 more
openaire +2 more sources
A review on lecithin:cholesterol acyltransferase deficiency
Clinical Biochemistry, 2015Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme which esterifies cholesterol, and plays a key role in the metabolism of high-density lipoprotein cholesterol (HDL-C). Genetic disorders of LCAT are associated with lipoprotein abnormalities including low levels of HDL-C and presence of lipoprotein X, and clinical features mainly corneal ...
Ramesh, Saeedi, Min, Li, Jiri, Frohlich
openaire +2 more sources
Serine carboxypeptidase-like acyltransferases
Phytochemistry, 2004In plant secondary metabolism, an alternative pathway of ester formation is facilitated by acyltransferases accepting 1-O-beta-acetal esters (1-O-beta-glucose esters) as acyl donors instead of coenzyme A thioesters. Molecular data indicate homology of these transferases with hydrolases of the serine carboxypeptidase type defining them as serine ...
Carsten, Milkowski, Dieter, Strack
openaire +2 more sources
Purification and Characterization of Lecithin:Cholesterol Acyltransferase
Scandinavian Journal of Clinical and Laboratory Investigation, 1978The purification of lecithin:cholesterol acyltransferase (LCAT] from human plasma is reported. Hydroxylapatite fractions were approximately 16,000 fold purified over the starting plasma and were free of high-density lipoprotein (HDL) and albumin.
E, Gustow, K G, Varma, L A, Soloff
openaire +2 more sources
Lysophospholipid acyltransferases
Current Opinion in Lipidology, 2012Over the past several years, many more isoforms for the same enzymes, specifically for 1-acylglycerol-3-phosphate O-acyltransferases (AGPATs), have been cloned and studied. In this review, we summarize their biochemical features and discuss their functional role.The most significant role of these AGPATs appeared from our observation of AGPAT2 in the ...
openaire +2 more sources
Structure and Function of Carnitine Acyltransferases
Annals of the New York Academy of Sciences, 2004Abstract: Carnitine acyltransferases catalyze the exchange of acyl groups between carnitine and coenzyme A (CoA). These enzymes include carnitine acetyltransferase (CrAT), carnitine octanoyltransferase (CrOT), and carnitine palmitoyltransferases (CPTs).
Gerwald, Jogl +2 more
openaire +2 more sources