Results 261 to 270 of about 58,529 (305)
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Lysophospholipid acyltransferases
Current Opinion in Lipidology, 2012Over the past several years, many more isoforms for the same enzymes, specifically for 1-acylglycerol-3-phosphate O-acyltransferases (AGPATs), have been cloned and studied. In this review, we summarize their biochemical features and discuss their functional role.The most significant role of these AGPATs appeared from our observation of AGPAT2 in the ...
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Structure and Function of Carnitine Acyltransferases
Annals of the New York Academy of Sciences, 2004Abstract: Carnitine acyltransferases catalyze the exchange of acyl groups between carnitine and coenzyme A (CoA). These enzymes include carnitine acetyltransferase (CrAT), carnitine octanoyltransferase (CrOT), and carnitine palmitoyltransferases (CPTs).
Gerwald, Jogl +2 more
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A protein cofactor of lecithin:Cholesterol acyltransferase
Biochemical and Biophysical Research Communications, 1972Abstract The effect of proteins isolated from human high density lipoprotein on cholesterol esterification by purified lecithin:cholesterol acyltransferase in the presence of dispersed lipids was studied. One of the major proteins present gave a maximal rate of esterification similar to that found with the native lipoprotein.
C J, Fielding, V G, Shore, P E, Fielding
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Mammalian acyl-CoA:cholesterol acyltransferases
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000Cholesterol, the chief sterol found in vertebrates, exists both as a free sterol and as a component of cholesterol esters, which are synthesized by acyl-CoA:cholesterol acyltransferase (ACAT) enzymes. Considerable knowledge concerning cholesterol ester metabolism has accumulated during the past century. However, rapid advances have occurred in the past
K F, Buhman, M, Accad, R V, Farese
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Lecithin:retinol acyltransferase in ARPE-19
Experimental Eye Research, 2005The purpose of this study is to investigate if a readily available cell line (APRE-19) may be used to study in vitro function of visual cycle enzymes such as lecithin:retinol acyltransferase (LRAT). Cells incubated with exogenous retinol accumulated intracellular all-trans retinol and all-trans retinyl ester.
Simon G, Trevino +3 more
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Inhibition of acyltransferase in lymphocytes by concanavalin A
Biochimica et Biophysica Acta (BBA) - General Subjects, 1980The effects of concanavalin A and succinylated concanavalin A on the transformation of mouse splenic lymphocytes, and on early biochemical events in the transformation, were compared. 1. The transformation of lymphocytes is biphasic with respect to concanavalin A concentration with optimal activation at about 1 microgram/ml.
P, Dobson, A, Mellors
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Acyltransferases and Triacylglycerols
2018Glycerolipids, by far the largest group of plant lipids, are structurally based on glycerol. This group includes glycodiacylglycerols, phospholipids, and acylglycerols such as triacylglycerol. The properties of the triacylglycerols depend on the fatty acids esterified with each of the three hydroxyl groups of glycerol.
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2003
The invention relates to polypeptides with lipase/acyltransferase activity, comprising an amino acid sequence, which ,< has at least 49° % similarity to the sequence given in SEQ ID NO. 2, also to polypeptides, which exhibit this activity, to nucleic acids (genes), which code for said polypeptides, to vectors, which contain nucleic acids that code ...
Weiss, Albrecht +3 more
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The invention relates to polypeptides with lipase/acyltransferase activity, comprising an amino acid sequence, which ,< has at least 49° % similarity to the sequence given in SEQ ID NO. 2, also to polypeptides, which exhibit this activity, to nucleic acids (genes), which code for said polypeptides, to vectors, which contain nucleic acids that code ...
Weiss, Albrecht +3 more
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Molecular recognition in carnitine acyltransferases
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 1989We are designing and synthesizing rigid guests to probe the topography of the carnitine acyltransferases, regulatory enzymes in lipid metabolism. Our designs are based on structural studies of substrates and possible molecular mechanisms of enzymatic activity. Recent X-ray, 1H NMR, and force-field computational studies on carnitine and acetylcarnitine,
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