Results 21 to 30 of about 72,098 (338)

The Very Long Chain Fatty Acid (C26:25OH) Linked to the Lipid A Is Important for the Fitness of the Photosynthetic Bradyrhizobium Strain ORS278 and the Establishment of a Successful Symbiosis with Aeschynomene Legumes

Frontiers in Microbiology, 2017
In rhizobium strains, the lipid A is modified by the addition of a very long-chain fatty acid (VLCFA) shown to play an important role in rigidification of the outer membrane, thereby facilitating their dual life cycle, outside and inside the plant.
Nicolas Busset, Flaviana Di Lorenzo, Angelo Palmigiano, Luisa Sturiale, Frederic Gressent, Joël Fardoux, Djamel Gully, Clémence Chaintreuil, Antonio Molinaro, Alba Silipo, Eric Giraud   +10 more
doaj   +1 more source

Chemical Synthesis of Trans 8-Methyl-6-Nonenoyl-CoA and Functional Expression Unravel Capsaicin Synthase Activity Encoded by the Pun1 Locus

Molecules, 2022
Capsaicin, produced by diverse Capsicum species, is among the world’s most popular spices and of considerable pharmaceutical relevance. Although the capsaicinoid biosynthetic pathway has been investigated for decades, several biosynthetic steps have ...
Raika Milde, Arianne Schnabel, Toni Ditfe, Wolfgang Hoehenwarter, Carsten Proksch, Bernhard Westermann, Thomas Vogt   +6 more
doaj   +1 more source

Sequence‐Based Prediction of Promiscuous Acyltransferase Activity in Hydrolases

Angewandte Chemie, 2020
Certain hydrolases preferentially catalyze acyl transfer over hydrolysis in an aqueous environment. However, the molecular and structural reasons for this phenomenon are still unclear.
H. Müller, Ann‐Kristin Becker, G. Palm, L. Berndt, Christoffel P. S. Badenhorst, Simon P. Godehard, L. Reisky, M. Lammers, U. Bornscheuer   +8 more
semanticscholar   +1 more source

Sex differences in plasma cholesterol-esterifying activity in rats

Journal of Lipid Research, 1967
Esterification of free cholesterol was investigated after incubation at 37°C of plasma from immature and adult rats of both sexes kept on stock, fat-free, or cholesterol-supplemented diets.
Lilla Aftergood, Roslyn B. Alfin-Slater
doaj   +1 more source

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

Nature Communications, 2018
Lipid droplet (LD) accumulation is a now well-recognised hallmark of cancer. However, the significance of LD accumulation in colorectal cancer (CRC) biology is incompletely understood under chemotherapeutic conditions.
A. Cotte, V. Aires, Maxime Fredon, E. Limagne, V. Derangère, M. Thibaudin, Étienne Humblin, A. Scagliarini, Jean-Paul Pais de Barros, P. Hillon, F. Ghiringhelli, Dominique Delmas   +11 more
semanticscholar   +1 more source

Expression of mouse MGAT in Arabidopsis results in increased lipid accumulation in seeds

Frontiers in Plant Science, 2015
Worldwide demand for vegetable oil is projected to double within the next thirty years due to increasing food, fuel and industrial requirements. There is therefore great interest in metabolic engineering strategies that boost oil accumulation in plant ...
Anna eEl Tahchy, Anna eEl Tahchy, James Robertson Petrie, James Robertson Petrie, Pushkar eShrestha, Pushkar eShrestha, Thomas eVanhercke, Thomas eVanhercke, Surinder eSingh, Surinder eSingh   +9 more
doaj   +1 more source

Rational Design for Enhanced Acyltransferase Activity in Water Catalyzed by the Pyrobaculum calidifontis VA1 Esterase

Microorganisms, 2021
Biocatalytic transesterification is commonly carried out employing lipases in anhydrous organic solvents since hydrolases usually prefer hydrolysis over acyl transfer in bulk water.
Amanda Staudt, Henrik Terholsen, Jasmin Kaur, Henrik Müller, Simon P. Godehard, Ivaldo Itabaiana, Ivana C. R. Leal, Uwe T. Bornscheuer   +7 more
doaj   +1 more source

Acyl-coenzyme A:cholesterol acyltransferases [PDF]

American Journal of Physiology-Endocrinology and Metabolism, 2009
The enzymes acyl-coenzyme A (CoA):cholesterol acyltransferases (ACATs) are membrane-bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form cholesteryl esters. In mammals, two isoenzymes, ACAT1 and ACAT2, encoded by two different genes, exist.
Ta-Yuan, Chang, Bo-Liang, Li, Catherine C Y, Chang, Yasuomi, Urano   +3 more
openaire   +2 more sources

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

mBio, 2018
Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii, although these genes had been considered dispensable on the basis of the
Richard C. White, Felizza F. Gunderson, Jessica Y. Tyson, Katherine H. Richardson, Theo J. Portlock, James A. Garnett, Nicholas P. Cianciotto   +6 more
doaj   +1 more source

Functional Characterization of a Hydroxyacid/Alcohol Hydroxycinnamoyl Transferase Produced by the Liverwort Marchantia emarginata

Molecules, 2017
The aerial organs of most terrestrial plants are covered by a hydrophobic protective cuticle. The main constituent of the cuticle is the lipid polyester cutin, which is composed of aliphatic and aromatic domains.
Ping-Ping Wang, Hui Liu, Shuai Gao, Ai-Xia Cheng   +3 more
doaj   +1 more source