Results 191 to 200 of about 24,285 (335)

Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function. [PDF]

Biomolecules
Volpicella M, Sgobba MN, Laera L, Francavilla AL, De Luca DI, Guerra L, Pierri CL, De Grassi A.   +7 more
europepmc   +1 more source

HYPK‐Related Neurodevelopmental Syndrome: Case Report of Intellectual Disability, Developmental Delay, and Dysmorphic Features

Clinical Genetics, EarlyView.
We present the first published case of HYPK‐related neurodevelopmental disorder in a male proband with atypical facies, developmental delay, and autism spectrum disorder– like features. HYPK is a part of the NatA complex, like NAA10 and NAA15, with dysfunction leading to similar but milder features to those of Ogden Syndrome.
Rahi Patel, Rikhil Makwana, Elaine Marchi, Ziyi Fan, Erin Falsey, Beatriz Menendez, Philip Giampietro, Ingrid M. Wentzensen, Tzung‐Chien Hsieh, Shu‐ou Shan, Gholson J. Lyon   +10 more
wiley   +1 more source

Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.

, 1979
Dhirendra L. Nandi, Samuel V. Lucas, L. T. Webster   +2 more
openalex   +1 more source

Recent Progress in <i>N</i>-Acylethanolamine Research: Biological Functions and Metabolism Regulated by Two Distinct <i>N</i>-Acyltransferases: cPLA₂ε and PLAAT Enzymes. [PDF]

Int J Mol Sci
Uyama T, Sasaki S, Okada-Iwabu M, Murakami M.   +3 more
europepmc   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

Cell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai, Jialei Hua, Donghua Meng, Yue Xu, Benfu Zhong, Miao Liu, Zhaosong Wang, Wei Zhou, Liming Liu, Hailong Wang, Yang Liu, Lifang Li, Xiuju Chen, Yueguo Li   +13 more
wiley   +1 more source

Factors affecting the acyl selectivities of acyltransferases in Escherichia coli.

, 1976
Harumi Okuyama, Kenneth M. Yamada, Hiroh Ikezawa, Salih J. Wakil   +3 more
openalex   +1 more source

Physiological and biochemical effects of different expression of acyl-CoA: lysophosphatidylethanolamine acyltransferases encoding genes observed in arabidopsis plants cultivated under low and standard temperatures. [PDF]

BMC Plant Biol
Jasieniecka-Gazarkiewicz K, Klińska-Bąchor S, Banaś A.   +2 more
europepmc   +1 more source

Plasma sphingolipids predict advanced liver fibrosis development in patients with type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Patients with type 2 diabetes (T2D) are at an elevated risk of developing metabolic dysfunction‐associated steatotic liver disease (MASLD), with a significant likelihood of progression to advanced liver fibrosis (AF)—a stage linked to adverse outcomes.
Sarah Béland‐Bonenfant, Damien Denimal, Jean‐Paul Pais‐de‐Barros, Hélène Choubley, Alexia Rouland, Isabelle Simoneau, Laurence Duvillard, Ludwig‐Serge Aho‐Glélé, Benjamin Bouillet, Jean‐Michel Petit, Bruno Vergès   +10 more
wiley   +1 more source

Structural unification of diverse transmembrane acyltransferases reveals a conserved fold for the transmembrane acyl transferase (TmAT) superfamily. [PDF]

J Biol Chem
Kinniment-Williams BE, Jurgeleviciute V, West DT, Herman R, Blaza JN, van der Woude MW, Thomas GH.   +6 more
europepmc   +1 more source

Metabolic dysfunction‐associated steatotic liver disease, insulin resistance and hepatocellular carcinoma: A deadly triad

European Journal of Clinical Investigation, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a major global cause of liver disease, driven by obesity and insulin resistance (IR). IR promotes hepatic lipid accumulation, inflammation and mitochondrial dysfunction, accelerating MASLD progression to fibrosis, cirrhosis and hepatocellular carcinoma (HCC).
Alfredo Caturano, Enes Erul, Roberto Nilo, Davide Nilo, Vincenzo Russo, Luca Rinaldi, Carlo Acierno, Erman Akkus, Katerina Koudelkova, Federica Cerini, Alessandro Rizzo, Ferdinando Carlo Sasso, Leonilde Bonfrate, Antonio Giordano, Hatime Arzu Yaşar, Caterina Conte   +15 more
wiley   +1 more source