Results 191 to 200 of about 11,126 (242)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

A tailored enzyme cascade facilitates DNA-encoded library technology and gives access to a broad substrate scope

Buller R, Schaub D, Lessing A, Meyer F, Eichenberger M, von Haugwitz G, Stockinger P, Gloger A, Scheuermann J.   +8 more
europepmc   +1 more source

Acyl-CoA: lysophosphatidylcholine acyltransferase from diatom P. Tricornutum efficiently remodels phosphatidylcholine containing polyunsaturated fatty acids. [PDF]

Sci Rep
Jasieniecka-Gazarkiewicz K, Połońska A, Gong Y, Banaś A.   +3 more
europepmc   +1 more source

Tomato‐Soy Juice Reduces Inflammation and Modulates the Urinary Metabolome in Adults With Obesity

Molecular Nutrition &Food Research, Volume 70, Issue 5, 12 March 2026.
Compared to pre‐intervention, consuming a tomato‐soy juice (54 mg lycopene, 189 mg soy isoflavones/d) reduced levels of inflammatory cytokines (IL‐5, IL‐12p70, and GM‐CSF, with TNF‐alpha trending downward), increased plasma lycopene and urinary soy isoflavone metabolites, and altered the urinary metabolome. ABSTRACT Chronic, low‐grade inflammation is a
Maria J. Sholola, Jenna Miller, Emma A. Bilbrey, Janet A. Novotny, David M. Francis, Thomas A. Mace, Jessica L. Cooperstone   +6 more
wiley   +1 more source

Detailed composition of wax esters in mouse sebum and the involvement of FAR2 and AWAT2. [PDF]

iScience
Kuribayashi K, Jojima K, Yamamoto M, Takeda M, Kihara A.   +4 more
europepmc   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Secondary Metabolites in Plants. [PDF]

Plants (Basel)
Palazon J, Alcalde MA.
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Herbgenomics: Unraveling natural product biosynthesis in traditional Chinese medicine. [PDF]

Chin Herb Med
Wang J, Song J, Chen S, Xu Z.
europepmc   +1 more source

Toward the Chemoenzymatic Synthesis of DNA-Encoded Libraries. [PDF]

ACS Cent Sci
Schaub D, Lessing A, von Haugwitz G, Meyer F, Scheuermann J, Buller R.   +5 more
europepmc   +1 more source