Results 51 to 60 of about 24,285 (335)

Global, site-specific analysis of neuronal protein S-acylation [PDF]

, 2017
Protein S-acylation (palmitoylation) is a reversible lipid modification that is an important regulator of dynamic membrane-protein interactions. Proteomic approaches have uncovered many putative palmitoylated proteins however, methods for comprehensive ...
Choudhary, J.S., Collins, M.O., Woodley, K.T.   +2 more
core   +1 more source

Effects of impaired steryl ester biosynthesis on tomato growth and developmental processes

Frontiers in Plant Science, 2022
Steryl esters (SE) are stored in cytoplasmic lipid droplets and serve as a reservoir of sterols that helps to maintain free sterols (FS) homeostasis in cell membranes throughout plant growth and development, and provides the FS needed to meet the high ...
Alma Burciaga-Monge, Joan Manel López-Tubau, Natalie Laibach, Cuiyun Deng, Albert Ferrer, Albert Ferrer, Teresa Altabella, Teresa Altabella   +7 more
doaj   +1 more source

Yeast Gup1(2) proteins are homologues of the Hedgehog Morphogens Acyltransferases HHAT(L): facts and implications [PDF]

, 2016
In multiple tissues, the Hedgehog secreted morphogen activates in the receiving cells a pathway involved in cell fate, proliferation and differentiation in the receiving cells. This pathway is particularly important during embryogenesis. The protein HHAT
Amanai, Chang, Chong, Kumar, Lorenz, Micchelli, Palková, Palková, Roelants, Verduyckt, Zhang, Zhang, Zhang, Zupan   +13 more
core   +2 more sources

Oligomerization of DHHC Protein S-Acyltransferases [PDF]

Journal of Biological Chemistry, 2013
The formation of dimers or higher-order oligomers is a property of numerous integral membrane proteins, including ion channels, transporters, and receptors. In this study, we examined whether members of the DHHC-S-acyltransferase family oligomerize in intact cells and in vitro.
Maurine E. Linder, Jianbin Lai
openaire   +3 more sources

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Identification of Three Genes Encoding for the Late Acyltransferases of Lipid A in Cronobacter sakazakii

Marine Drugs, 2013
Lipid A, the hydrophobic anchor of lipopolysaccharide, is an essential component in the outer membrane of most Gram-negative bacteria. Food-borne pathogen Cronobacter sakazakii synthesizes two lipid A species, differing by the length of the secondary ...
Wen Guo, Chan Zhang, Xiaoyuan Wang, Guanjun Tao, Liping Cai, Yanyan Li   +5 more
doaj   +1 more source

GhGPAT12/25 Are Essential for the Formation of Anther Cuticle and Pollen Exine in Cotton (Gossypium hirsutum L.)

Frontiers in Plant Science, 2021
Glycerol-3-phosphate acyltransferases (GPATs), critical for multiple biological processes like male fertility, have been extensively characterized. However, their precise functions and underlying regulatory mechanism in cotton anther development are ...
Meng Zhang, Hengling Wei, Pengbo Hao, Aimin Wu, Qiang Ma, Jingjing Zhang, Hantao Wang, Xiaokang Fu, Liang Ma, Jianhua Lu, Shuxun Yu   +10 more
doaj   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Differential intracellular management of fatty acids impacts on metabolic stress-stimulated glucose uptake in cardiomyocytes

Scientific Reports, 2023
Stimulation of glucose uptake in response to ischemic metabolic stress is important for cardiomyocyte function and survival. Chronic exposure of cardiomyocytes to fatty acids (FA) impairs the stimulation of glucose uptake, whereas induction of lipid ...
Ettore Vanni, Karina Lindner, Anne-Claude Gavin, Christophe Montessuit   +3 more
doaj   +1 more source

Storage oil hydrolysis during early seedling growth [PDF]

, 2009
Storage oil breakdown plays an important role in the life cycle of many plants by providing the carbon skeletons that support seedling growth immediately following germination.
Andrews, Anne-Laure Quettier, Athenstaedt, Athenstaedt, Baker, Beisson, Chia, Ducharme, Eastmond, Eastmond, Eastmond, El-Kouhen, Fernandez, Frandsen, Fuchs, Fuchs, Ghosh, Ghosh, Graham, Grönke, Gupta, Hayashi, Hellyer, Hills, Hills, Hills, Huang, Ishiguro, Jennens, Jolivet, Kurat, Lass, Lin, Lin, Maeshima, Matsui, May, Mhaske, Mukherjee, Murphy, Murphy, Ncube, Noll, Ohlrogge, Ollis, Peter J. Eastmond, Poxleitner, Quettier, Robenek, Rydel, Schweiger, Siloto, Somerville, Stahl, Ubersax, Wanner, Zimmermann   +56 more
core   +1 more source