Results 51 to 60 of about 32,867 (333)
Nature Communications, 2021 Double membrane vesicles (DMV) are used as replication organelles by several RNA viruses. Applying proteomics and lipidomics, Tabata and Prasad et al.
Keisuke Tabata +25 more
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Membrane Topology of Hedgehog Acyltransferase [PDF]
Journal of Biological Chemistry, 2015 Hedgehog acyltransferase (Hhat) is a multipass transmembrane enzyme that mediates the covalent attachment of the 16-carbon fatty acid palmitate to the N-terminal cysteine of Sonic Hedgehog (Shh). Palmitoylation of Shh by Hhat is critical for short and long range signaling.
Armine Matevossian, Marilyn D. Resh
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Update on glycerol-3-phosphate acyltransferases: the roles in the development of insulin resistance
Nutrition & Diabetes, 2018 Glycerol-3-phosphate acyltransferase (GPAT) is the rate-limiting enzyme in the de novo pathway of glycerolipid synthesis. It catalyzes the conversion of glycerol-3-phosphate and long-chain acyl-CoA to lysophosphatidic acid.
Jing Yu +5 more
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Scientific Reports, 2022 BAHD superfamily acyltransferases play an important role in catalyzing and regulating secondary metabolism in plants. Despite this, there is relatively little information regarding the BAHD superfamily in barley.
Zhen Yuan +7 more
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Journal of Lipid Research, 2019 Leukotrienes (LTs) are autacoids derived from the precursor arachidonic acid (AA) via the action of five-lipoxygenase (5-LO). When inflammatory cells are activated, 5-LO translocates to the nuclear membrane to initiate oxygenation of AA released by ...
R. Murphy, G. Folco
semanticscholar +1 more source
Oligomerization of DHHC Protein S-Acyltransferases [PDF]
Journal of Biological Chemistry, 2013 The formation of dimers or higher-order oligomers is a property of numerous integral membrane proteins, including ion channels, transporters, and receptors. In this study, we examined whether members of the DHHC-S-acyltransferase family oligomerize in intact cells and in vitro.
Maurine E. Linder, Jianbin Lai
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Identification of Giardia lamblia DHHC proteins and the role of protein S-palmitoylation in the encystation process. [PDF]
PLoS Neglected Tropical Diseases, 2014 Protein S-palmitoylation, a hydrophobic post-translational modification, is performed by protein acyltransferases that have a common DHHC Cys-rich domain (DHHC proteins), and provides a regulatory switch for protein membrane association. In this work, we
María C Merino +4 more
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Effects of impaired steryl ester biosynthesis on tomato growth and developmental processes
Frontiers in Plant Science, 2022 Steryl esters (SE) are stored in cytoplasmic lipid droplets and serve as a reservoir of sterols that helps to maintain free sterols (FS) homeostasis in cell membranes throughout plant growth and development, and provides the FS needed to meet the high ...
Alma Burciaga-Monge +7 more
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Marine Drugs, 2013 Lipid A, the hydrophobic anchor of lipopolysaccharide, is an essential component in the outer membrane of most Gram-negative bacteria. Food-borne pathogen Cronobacter sakazakii synthesizes two lipid A species, differing by the length of the secondary ...
Wen Guo +5 more
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Acyl-coenzyme A:cholesterol acyltransferases [PDF]
American Journal of Physiology-Endocrinology and Metabolism, 2009 The enzymes acyl-coenzyme A (CoA):cholesterol acyltransferases (ACATs) are membrane-bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form cholesteryl esters. In mammals, two isoenzymes, ACAT1 and ACAT2, encoded by two different genes, exist.
Bo-Liang Li +3 more
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