Results 141 to 150 of about 32,386 (229)

Severe, Resistant Generalized Pustular Psoriasis-Associated Inflammatory Syndrome Successfully Treated With Adalimumab: A Case Report. [PDF]

Cureus
Bourousis E, Kotzamani MT, Maritsi DN.
europepmc   +1 more source

Effect of Disease Extent on Leucine‐Rich α2‐Glycoprotein as a Marker for Endoscopic Mucosal Healing in Patients With Ulcerative Colitis

JGH Open, Volume 10, Issue 2, February 2026.
ABSTRACT Aims To determine whether the performance of leucine‐rich α2‐glycoprotein (LRG) as a biomarker for disease activity in patients with ulcerative colitis (UC) may depend on the extent of the disease. Methods and Results We evaluated the correlation between various biomarkers, including the serum biomarker LRG, and endoscopic activity in 171 ...
Shogo Kitahata, Mai Saito, Yuka Kimura, Ayaka Nakamura, Toru Usui, Kanako Kato, Kei Onishi, Kozue Kanemitsu‐Okada, Tomoe Kawamura, Hideko Ohama, Taira Kuroda, Junko Matsuoka, Fujimasa Tada, Hideki Miyata, Atsushi Hiraoka, Eiji Tsubouchi, Tomoyuki Ninomiya, Yoichi Hiasa   +17 more
wiley   +1 more source

Savings from biosimilars and Medicare formulary access. [PDF]

Health Aff Sch
Axelsen K, Courmier D, Bai G, Maini L.
europepmc   +1 more source

Tumor Necrosis Factor (TNF)-Alpha Inhibitors in Hidradenitis Suppurativa: A Systematic Review of Inflammatory Markers and Alternative Monitoring Strategies. [PDF]

Cureus
R R, Mann RS, Chopra I, Kilic A, Saxena A, Khan B, Khan S.   +6 more
europepmc   +1 more source

Anti‐tumor necrosis factor‐α monotherapy versus combo therapy with immunosuppressant in pediatric inflammatory bowel disease: A real‐life study

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 454-464, February 2026.
Abstract Objectives The aim of the study is to evaluate the efficacy of anti‐tumor necrosis factor (TNF)‐α monotherapy versus combination anti‐TNF‐α and immunosuppressive therapy. Methods A single‐center, retrospective, observational study was conducted on inflammatory bowel disease (IBD) children.
Flora Fedele, Massimo Martinelli, Caterina Strisciuglio, Elena Scarpato, Annamaria Staiano, Erasmo Miele   +5 more
wiley   +1 more source

Engineering Extended Release Profiles for Biologic Formulations via Chemical Cross-Linking of Poloxamer 407 Hydrogels. [PDF]

ACS Omega
Park J, Lin YJ, Dutta K, Forster S, Okoh G, Tian Y, Liang Y.   +6 more
europepmc   +1 more source

Using machine learning to predict clinical remission with exclusive enteral nutrition in pediatric Crohn disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 465-476, February 2026.
Abstract Objectives Exclusive enteral nutrition (EEN) is a first‐line treatment for induction of remission in luminal pediatric Crohn disease (pCD). However, as the efficacy of EEN varies from patient to patient, there is a need to distinguish between responders and nonresponding patients. This study had two aims.
Ricardo G. Suarez Suarez, Daniel G. McClement, Roberto Vega, Hien Q. Huynh, Ayub Shaikh, Anthony Otley, Kevan Jacobson, Mary Sherlock, David R. Mack, Colette Deslandres, Wael El‐Matary, Eileen Crowley, Jennifer deBruyn, Thomas Walters, Anne M. Griffiths, Russell Greiner, Eytan Wine, The Canadian Children IBD Network, Jeff Critch, Lara Hart, Rilla Schneider, Kevin Bax, Eric I. Benchimol   +22 more
wiley   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Interpretable Artificial Neural Network Models for Predicting Anti-Adalimumab Immune Complex and Serum Drug Level in Crohn's Disease: A Proof-of-Concept Study. [PDF]

Pharmaceutics
Genaro LM, Carron J, Lourenço GJ, Nagasako CK, Reis GFSR, Camargo MG, Oliveira PSP, Lima CSP, Ayrizono MLS, Azevedo AT, Leal RF.   +10 more
europepmc   +1 more source

Therapeutic Effects of Noninvasive Electrical Stimulation in Combination Transplantation of Human Adipose‐Derived Stem Cells‐Derived Dopaminergic Neuron on the Monkey Model of Parkinson's Disease

MedComm, Volume 7, Issue 2, February 2026.
Our results showed that noninvasive electrical stimulation (NES) alone or in combination with human adipose‐derived stem cells (hADSCs)‐induced dopaminergic neuron (NES‐DN) improved the behavioral deficits and pathological features of the MPTP‐induced PD monkey model.
Chunhui Huang, Shane Gao, Xiao Zheng, Xichen Song, Jiaxi Wu, Kai Liao, Jiawei Li, Yingqi Lin, Caijuan Li, Yaqun Lu, Jiahao Feng, Huiyi Wei, Lu Wang, Hao Xu, Wei Wang, Yizhi Chen, Jianhao Wu, Jiale Gao, Junzhu Song, Chunxiang Shi, Jun Zhang, Sen Yan   +21 more
wiley   +1 more source