Results 191 to 200 of about 66,826 (280)

Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review

open access: yesObesity Reviews, EarlyView.
ABSTRACT Inflammatory bowel disease is a chronic inflammatory disorder affecting the gastrointestinal tract. It mainly comprises of Crohn's disease and ulcerative colitis. Its global prevalence has risen simultaneously with overweight and obesity among children and young people over the last decades.
Razan Algarni   +2 more
wiley   +1 more source

Erythrokeratodermia‐Cardiomyopathy Syndrome: Expanding the DSP Mutational Spectrum Beyond Proline Substitutions

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Erythrokeratodermia cardiomyopathy (EKC) syndrome is a rare autosomal dominant disorder characterized by generalized erythrokeratoderma and progressive dilated cardiomyopathy, caused by pathogenic variants in the SR6 domain of desmoplakin (DSP).
Sepideh Hamzehlou   +7 more
wiley   +1 more source

Comorbidities of Pediatric Patients With Hidradenitis Suppurativa in the Emergency Department Setting: A Cross‐Sectional Study

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) often leads to painful episodes requiring emergency department (ED) care, yet little is known about the comorbidities associated with these visits in pediatric patients. This study examined the Nationwide Emergency Department Sample (NEDS) from 2006 to 2019, identifying HS diagnoses via ICD‐9 and ICD‐10 codes to ...
Rahwa Hailemichael   +5 more
wiley   +1 more source

Fatal Chronic Varicella‐Zoster Viral Infection in a Young Man With Chediak–Higashi Syndrome

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Chediak–Higashi syndrome (CHS) is a rare autosomal recessive primary immunodeficiency characterized by partial oculocutaneous albinism, neurologic involvement, and a predisposition to severe infections. Patients are particularly susceptible to developing hemophagocytic lymphohistiocytosis (HLH), which significantly worsens prognosis. We report
Albane Badet   +4 more
wiley   +1 more source

Antigen binding triggers long-range conformational changes in monoclonal antibodies. [PDF]

open access: yesFront Immunol
Bianchi D   +6 more
europepmc   +1 more source

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne   +7 more
wiley   +1 more source

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