Results 141 to 150 of about 22,445 (222)

Characterization of the D8P1C1 Anti-ADAM17 Inhibitory Monoclonal Antibody and Generation of Its Bispecific T-Cell Engager Derivative. [PDF]

Int J Mol Sci
Saha N, Lee SG, de Stanchina E, Mendoza RP, Veach DR, Nikolov DB.   +5 more
europepmc   +1 more source

Pathway landscape and regulatory networks of epigenetically modified Breast Cancer genes [PDF]

Epigenetic changes are a key regulator of gene expression in different cancer histotypes. After investigating the differentially expressed genes upon treatment with a demethylating agent, e.g.
Capobianco, Enrico, Cinti, Caterina, El Baroudi, Mariama, La Sala, Dario   +3 more
core  

Prognostic value of miR-26b-5p in prostate cancer and its regulatory effect on tumor progression. [PDF]

World J Surg Oncol
Gao C, Lou L, Miao L, Ma S, Liu C, Cao X.   +5 more
europepmc   +1 more source

The Potential of A Disintegrin and Metalloproteinase (ADAM) Proteins as Clinically Relevant Biomarkers in Colorectal Cancer: A Comprehensive Analysis. [PDF]

Cancers (Basel)
Romanowicz A, Łukaszewicz-Zając M, Mroczko B.   +2 more
europepmc   +1 more source

Thioredoxin-80 is a product of alpha-secretase cleavage that inhibits amyloid-beta aggregation and is decreased in Alzheimer's disease brain [PDF]

, 2012
Akterin, Susanne, Gil Bea, Francisco Javier, Gutiérrez Rodríguez, Ángel, Persson, Torbjörn   +3 more
core   +1 more source

Age-dependent induction of ER stress in retinal pigment epithelium impairs phagocytosis via ADAM17-dependent MERTK shedding. [PDF]

J Biol Chem
Yasuda H, Nakamura S, Shirakawa A, Kuse Y, Mori K, Shimazawa M.   +5 more
europepmc   +1 more source

Leukocytic ADAM10 and ADAM17 modulate disease severity and systemic outcome in bacterial and viral pneumonia. [PDF]

Eur Respir J
Aljohmani A, Herr C, Witzenrath M, Pätzold L, Bischoff M, Wartenberg P, Boehm U, Beisswenger C, Tian Q, Laschke MW, Hannig M, Lehr CM, Bals R, Schilling O, Yildiz D.   +14 more
europepmc   +1 more source

Genetic variations in AAK1 and ADAM17 associated with circulatory cytokines changes influence COVID-19 susceptibility and severity. [PDF]

Hum Genomics
Bouzid A, Elemam NM, Alsafar H, Venkatachalam T, Eldoahji L, Halabi N, Saleh MA, Talaat IM, Taneera J, Sulaiman N, Maghazachi AA, Hamid Q, Hamoudi R, Saber-Ayad M.   +13 more
europepmc   +1 more source

Longitudinal profiling of serum ADAM17 across clinical stages in multiple myeloma: a dynamic biomarker and its association with T cell alterations. [PDF]

Front Mol Biosci
Qu J, Li Y, Li C, Wu D, Cao Y, Xiao S, Bao X, Li Q, Chen Z, Chen L.   +9 more
europepmc   +1 more source

ADAM17, induced by Augmenter of Liver Regeneration via G protein-coupled receptor activation, transactivates epidermal growth factor-receptor and reduces classical IL-6 signaling. [PDF]

Cell Commun Signal
Voigt C, Menzel S, Dayoub R, Kubitza M, Schmutzler F, Buechler C, Eggenhofer E, Melter M, Weiss TS.   +8 more
europepmc   +1 more source