Cytokine gene polymorphisms of TNF, IFN-γ, and IL-12 as potential predictors in the onset of cervical disease in HR HPV-positive women with behavioral risk cofactors [PDF]
Introduction/Objective. The aim of this study was to investigate the distribution of genotypes and alleles of proinflammatory cytokines TNF, IFN-γ, and IL-12 and their effect on the development of a cervical illness and also to determine their associated
Tasić-Tomić Dijana +5 more
doaj +1 more source
Effect of mangosteen skin ethanol extract on streptozotocin-induced TNF-α expression
Introduction: Diabetes Mellitus (DM) is a significant health problem worldwide. DM with poor control of blood glucose levels can eventually cause pancreatic cell disorders, including a decrease in cell mass and function. Mangosteen rind contains xanthone
Novera Herdiani +3 more
doaj +1 more source
Background: This study investigates the efficiency of two different types of immunomodulators for the treatment of non-severe community-acquired pneumonia (CAP) and assesses their long-term effects.
Mikhail P Kostinov +5 more
doaj +1 more source
Molecular markers of cardiac fibrosis after myocardial infarction
Aim. To perform a screening for molecular markers of cardiac fibrosis upon myocardial infarction.Materials and Methods. We carried out echocardiography-guided endomyocardial biopsy of affected and intact interventricular septum segments of 7 patients ...
O. L. Barbarash +8 more
doaj +1 more source
TAK1: a potent tumour necrosis factor inhibitor for the treatment of inflammatory diseases [PDF]
Aberrant tumour necrosis factor (TNF) signalling is a hallmark of many inflammatory diseases including rheumatoid arthritis (RA), irritable bowel disease and lupus.
Juliane Totzke +3 more
doaj +1 more source
Bioinformatic analysis of differentially expressed genes in porcine intestinal epithelial cells infected with transmissible gastroenteritis virus [PDF]
Transmissible Gastroenteritis Virus (TGEV) infection is one of the leading causes of diarrhea in piglets. Intestinal immune system plays an important role in maintaining the intestinal mucosa"s integrity and resisting infection by pathogens. However, the
Xu-xuan ZHANG +7 more
doaj +1 more source
Sialadenosis is a dystrophic disease of the salivary glands parenchyma, which leads to secretory disorders and hypertrophy of salivary glands. Sialadenitis develops in cases of secondary inflammation. Standard methods and medications for the treatment of
T. B. Sultimova +4 more
doaj +1 more source
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F. +4 more
core +1 more source
Cytokines, reverse genetics and anti-cytokine therapy
Cytokines comprise the molecular language of communication between the cells, which is needed to maintain the homeostatic functions of the body (including the immune system) and mediate various diseases.
M. S. Drutskaya +9 more
doaj +1 more source
In Vitro Fertilization, Levels of Pro-Inflammatory Factors and Lipid Peroxidation [PDF]
Background Infertility is a problem concerning 10-15% of the individuals in the fertile period. This study investigated effects of proinflammatory factors as well as lipid hydroperoxides (LPO) levels upon in vitro fertilization (IVF) success.
Ferdag Yildizfer +12 more
doaj +1 more source

