Results 31 to 40 of about 1,230,752 (303)
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF [PDF]
, 2013 Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases.
Albanese CT +15 more
core +3 more sources
TNFR2: Role in Cancer Immunology and Immunotherapy
ImmunoTargets and Therapy, 2021 Yang Yang, Md Sahidul Islam, Yuanjia Hu, Xin Chen State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, SAR, 999078, People’s Republic of ChinaCorrespondence: Xin ChenState ...
Yang Y, Islam MS, Hu Y, Chen X
doaj
The effect of 6 weeks Tai chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2017 The aim of this study was to determine the effect of Tai Chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke.
منیژه نوروزیان +2 more
doaj +1 more source
Modulation of autocrine TNF-α-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogenactivated protein kinases in THP-1 monocytic cells [PDF]
, 2006 Matrix metalloproteinase 9 (MMP-9) is implicated in various physiological processes by its ability to degrade the extracellular matrix (ECM) and process multiple regulatory proteins. Normally, MMP-9 expression is tightly controlled in cells. Sustained or
Bogoyevitch +13 more
core +1 more source
Adipocyte ADAM17 plays a limited role in metabolic inflammation
Adipocyte, 2020 The role of ADAM17, its substrates, and its natural inhibitor has been well studied in the context of inflammation, including metabolic inflammation, with mixed results.
Joseph C. Lownik +4 more
doaj +1 more source
Viewpoint on handling anti-TNF failure in psoriasis [PDF]
, 2013 An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core +1 more source
Медицинская иммунология, 2014 . The main objective of this work was to identify allelic variants of cytokine genes at the polymorphic positions of G-308A TNFА, T-330G IL-2, С-590Т IL-4, С-703Т IL-5, and C-592A IL-10, and to assess their contribution to predisposition and resistance ...
V. V. Avdoshina +6 more
doaj +1 more source
Transmembrane TNF-dependent uptake of anti-TNF antibodies [PDF]
mAbs, 2017 TNF-α (TNF), a pro-inflammatory cytokine is synthesized as a 26 kDa protein, anchors in the plasma membrane as transmembrane TNF (TmTNF), and is subjected to proteolysis by the TNF-α converting enzyme (TACE) to release the 15 kDa form of soluble TNF (sTNF). TmTNF and sTNF interact with 2 distinct receptors, TNF-R1 (p55) and TNF-R2 (p75), to mediate the
Deora, Arun +17 more
openaire +2 more sources
TNF-α, An Inflammatory Path, Rerouted Through Alternate Medicinal Channels
Journal of Pharmacy and Bioallied SciencesIntroduction: This study emphasizes the efficacy of triphala as a therapeutic agent over inflammatory condition in hydrogen sulfide (H2 S) mediated inflammatory path in the presence of titanium (Ti) discs.
Shyam Sundar Shanker +4 more
doaj +1 more source
Медицинская иммунология, 2014 . Generalized forms of meningococcal infection (GFMI) are usually accompanied with apparent symptoms of systemic inflammatory response (SIRS). Systemic production of inflammatory cytokines, their accumulation in circulating blood and action on various ...
S. T. Akalovich +4 more
doaj +1 more source