Results 31 to 40 of about 948,306 (261)

Cytokine tatus in patients with recurrent herpes infection

Антибиотики и Химиотерапия, 2021
The study of the concentration of the main pro-inflammatory cytokines (IL-1β, IL-6 and TNF) in the blood serum of 48 patients with recurrent chronic herpesvirus infection was carried out.
A. S. Akmeeva, R. B. Zhamborova, A. Ya. Aloeva, A. M. Kakhidov, I. D. Abdulkadyrova, D. M. Altamirova, Z. A. Kambachokova, T. Sh. Tagirova, A. E. Elkham   +8 more
doaj   +1 more source

THE LEVELS OF SOLUBLE RECEPTOR OF TUMOR NECROSIS FACTOR P55, TNF, NEUTROPHIL-DERIVED ALPHA-DEFENSINS AND BOTH ISOFORMS OF INTERLEUKIN-8 IN THE BLOOD AND CEREBROSPINAL FLUID (CSF) FROM CHILDREN WITH GENERALIZED FORMS OF MENINGOCOCCAL INFECTION

Медицинская иммунология, 2014
. Generalized forms of meningococcal infection (GFMI) are usually accompanied with apparent symptoms of systemic inflammatory response (SIRS). Systemic production of inflammatory cytokines, their accumulation in circulating blood and action on various ...
S. T. Akalovich, N. N. Nashkevich, A. P. Kudin, A. A. Astapov, N. N. Voitenok   +4 more
doaj   +1 more source

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Welsch, Ulrich, Sommerhoff, Christian P., Gilles, Stefanie, Zahler, Stefan, Becker, Bernhard F.   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Roles Of Tumor Necrosis Factor In Animal Tissues : Review Article

Journal of Applied Veterinary Sciences, 2020
Inflammation is a particular portion of tissue response to harmful inflammogens roles of it with interleukins, and systemic effects of TNF. This response including different types of inflammatory cells like (neutrophils, macrophages, lymphocytes).
H.B.Al-sabaawy, Yasmeen J.M, Enas.S.M., E. Al.Hamdany   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Exploring the association between human cytomegalovirus, immunological and biochemical parameters in Iraqi women with polycystic ovary syndrome [PDF]

Exploration of Immunology
Aim: The current study was planned to assess the statistical correlation between seroprevalence of human cytomegalovirus (HCMV) and important inflammatory markers: tumor necrosis factor-alpha (TNF-α) and interleukin-18 (IL-18) within Iraqi women ...
Sura O. Yousif, Maha Diekan Abbas, Shatha M. Ali, Iman Khudhair Diwan, Sanar Muhyaddin, Jaleel Samanje   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

That Gut Feeling: The Role of Inflammatory Cytokines in Depression Among Patients with Inflammatory Bowel Disease

European Medical Journal Gastroenterology, 2020
There is mounting evidence of an associative link between inflammatory bowel disease (IBD) and clinical depression. In the first major treatise on the eponymous disease, Burrill Crohn himself noted that: “The number of cases of ileitis that have been ...
Brant J. Chapman , Graham B. Jones
doaj