Results 51 to 60 of about 948,306 (261)

Circulating Levels of Adipokines and TNF in Patients with and without Type 1 Diabetes

Journal of the Dow University of Health Sciences, 2013
Objective: The aim of this study was to evaluate circulating levels of adiponectin, resistin, visfatin and TNFin type1 diabetic children and young adolescents.
Anila Jaleel, Bilal Aheed, Shahila Jaleel, Adnan Zuberi   +3 more
doaj  

Mechanism investigation of Actinidia arguta total flavone on gout via network pharmacology and vivo experiments pharmacological verification

Open Life Sciences
To clarify the therapeutic targets and signaling pathways of Actinidia arguta total flavone (AATF) in gout treatment, we integrated network pharmacology and in vivo experiments.
Wang Yilin, Wang Shuang, Li Zhaoxia, Chen Xi, Zhang Chengyi, Han Xiaoxue, Wan Limei, Fan Suiqiang, Liu Yiting, Guo Ziyan, Huang Xiaoqiang, Xu Xiaoze, Zhou Xin, Xing Bingfeng   +13 more
doaj   +1 more source

Contribution of Toll-Like Receptors and the NLRP3 Inflammasome in Rheumatoid Arthritis Pathophysiology

ImmunoTargets and Therapy, 2021
Sarah Unterberger, Kevin A Davies, Srinivasa Bhargav Rambhatla, Sandra Sacre Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PS, UKCorrespondence: Sandra Sacre Tel +441273 872865Email s.sacre@bsms.ac.ukAbstract ...
Unterberger S, Davies KA, Rambhatla SB, Sacre S   +3 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Electric foot-shock stress drives TNF-alpha production in the liver of IL-6-deficient mice [PDF]

, 2004
Objectives: Accumulating evidence has shown that interleukin-6 (IL-6) has pleiotropic effects on a variety of biological functions, including its antiapoptotic potential during liver injury.
Chida, Y, Motomura, Y, Kubo, C, Sudo, N
core  

High TNF-alpha plasma levels and macrophages iNOS and TNF-alpha expression as risk factors for painful diabetic neuropathy

, 2011
Thomas Eko PurwataNeurology Department, Udayana University/Sanglah General Hospital, Denpasar, Bali, IndonesiaAbstract: Painful diabetic neuropathy (PDN) is one of the most common complications of diabetes mellitus.
Purwata TE, Thomas Purwata
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Evaluation of inflammatory response in patients undergoing surgical treatment for early and delayed femoral fractures

Archives of Medical Science, 2018
Introduction It has been shown that long bone fractures are correlated with the inflammatory response. In the initial injury, surgical reduction and fixation of fractures induce the immunoinflammatory response.
Mehdi Moghtadaei, Babak Otoukesh, Hamidreza Pazoki-Toroudi, Bahram Boddouhi, Ali Yeganeh   +4 more
doaj   +1 more source

TNF-α levels are upregulated in response to ischemia.

, 2020
Quantitative rtPCR analysis of relative TNF-α mRNA levels. Tissue was harvested (A) immediately, (B) after 24 hours of reperfusion, or (C) 5 days of reperfusion.
Young-Kwon Hong (158165), David P. Perrault (8284254), Gene K. Lee (8284257), Cynthia Sung (2935794), Antoun Bouz (8284260), Austin J. Pourmoussa (8284266), Alex K. Wong (8284275), Ketan M. Patel (8284272), Sun Young Park (2410558), Gene H. Kim (8284269), Roy Yu (8284263), Wan Jiao (1598995)   +11 more
core   +1 more source

Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease [PDF]

, 2011
We recently reported that expression levels of tumor necrosis factor (TNF) receptors, TNFR1 and TNFR2, are significantly changed in the brains and cerebral spinal cerebral fluid (CSF) with Alzheimer's disease (AD).
Blennow, Kaj,, Shen, Yong, Hampel, Harald, Rena Li, Hampel Harald, Prvulovic, David, Yong Shen, Wallin, Anders,, Jiang, Hong, David Prvulovic, Hong Jiang, Wallin, Anders, Kaj Blennow, Wallin Anders, Shen Yong, Anders Wallin, Li, Rena, Blennow Kaj, Jiang Hong, Prvulovic David, Harald Hampel, Blennow, Kaj, Li Rena   +22 more
core   +1 more source