Results 61 to 70 of about 948,306 (261)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Screening of the human tumor necrosis factor (TNF) gene and its receptor 1 (TNFR1) gene for DNA alterations and the subsequent investigation of these and an IL12p40 polymorphism for an association with paediatric tuberculosis [PDF]

, 2004
Includes bibliographical references (leaves 85-96).Infection with Mycobacterium tuberculosis is characterised by diverse outcomes; the majority of infected individuals remain well and yet others develop disease ranging from limited pulmonary tuberculosis
Lampel, Netanya
core   +1 more source

TNF-α levels and presence of SNP-308G/A of TNF-α gene in temporomandibular disorder patients

, 2022
Introduction: Temporomandibular disorder (TMD) refers to a group of conditions that compromise the harmonious movement and function of the temporomandibular joint, masticatory muscles, and associated structures.
Renata Silva Melo FERNANDES (12853596), Camilla Porto CAMPELLO (12833819), Elker Lene Santos de LIMA (12833822), Maria Tereza Cartaxo MUNIZ (12833828), Mirza PORTO (12853599)   +4 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

TNF-a and FGF immunohistochemical expressions and pathological evaluation of the duck's liver lesions in Mosul city [PDF]

Iraqi Journal of Veterinary Sciences
This research focuses on studying liver illnesses in ducks in Mosul city by analyzing the expression of TNF alpha and FGF proteins as indicators of inflammation and abnormal growths in the liver tissues samples were collected from duck liver in Mosul ...
Soadd M. Alhamdani, Ahmed N. Flayyih, Ayman A. Al-Alhially   +2 more
doaj   +1 more source

TNF-α production in response to LPS.

, 2016
(A) Comparison of basal levels of TNFA mRNA in granulocytes among healthy controls, Group A and Group B. (B) Comparison of fold increase of TNFA mRNA induced by simulation with 1 μg/mL LPS for indicated times.
Hideo Kimura (402027), Kazuhiko Ikeda (402025), Junko Kimura (402028), Kazuei Ogawa (402026), Tomoyuki Ono (212003), Meiwan Cao (2937600), Xiaomin Feng (402021), Yasuchika Takeishi (42692), Yuko Suzuki (279017), Hideyoshi Noji (402024), Yayoi Shikama (402022)   +10 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Gene sequences of TNF and INFα Cytokines in Cryptosporidium Co-infection with H-pylori of irritable bowel syndrome [PDF]

Journal of Bioscience and Applied Research
In this study, 100 whole blood samples were collected from patients having Cryptosporidiosis and co-infected with H pylori bacteria who attended Baghdad Teaching Hospital during the period from June 2022 to April 2023.
Basheer Nasralla, Nazar Mohammed, Salwa Muhsen   +2 more
doaj   +1 more source

Tumor nekrózis faktor (TNF) reverz jelátvitele

, 2015
A dolgozat a TNF szuper család tagjainak már ismert reverz jelátvitelének folyamatait foglalja össze. Áttekintést ad a TNF család tagjainak genetikai eltéréseinek, vagy túlzott funkcióinak betegségekkel való kapcsolatáról.gjBiológiaBSc ...
Bárány, Alexandra
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source