Results 81 to 90 of about 948,306 (261)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

GENETIC MARKERS OF MYOCARDIAL FIBROSIS: OPPORTUNITY TO PREDICT ADVERSE OUTCOMES IN AORTIC STENOSIS

Российский кардиологический журнал, 2018
Aim. To evaluate the influence of genetic markers of inflammation and fibrosis on survival rate of patients with non operated aortic stenosis (AS). The search for novel prognostically adverse factors in calcinated AS patients with none surgical treatment
Т. A. Tipteva, О. S. Chumakova, A. N. Brovkin, A. G. Nikitin, N. Е. Reznichenko, D. A. Zateyshchikov   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The phospho-barcode of RIPK1: complementarity or redundancy?

Molecular & Cellular Oncology, 2020
Receptor interacting serine/threonine kinase 1 (RIPK1) is the central mediator of tumor necrosis factor (TNF) signaling. It regulates both pro-survival/pro-inflammatory and cell death pathways.
Wenxian Wu, Björn Stork
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

TNF-α Expression Test (TET) for endotoxin detection.

, 2016
a). The TET was performed to detect endotoxin content in all GBMs upon exposure of HMDM to 25 and 50 μg/ml for 24 h. The differences in TNF-α expression in the presence and absence of polymyxin B sulfate (Poly-B) (10 μM) provided evidence of the presence
Peter Wick (435597), Sourav P. Mukherjee (3360884), Leon Newman (3360881), Bengt Fadeel (127548), Ester Vázquez (2465944), Melanie Kucki (2734537), Antonio E. Del Rio-Castillo (3360878), Neus Lozano (2054482), Kostas Kostarelos (276400)   +8 more
core   +1 more source

TNF-α expression and age in skin punch biopsies of healthy controls and PD patients.

, 2022
Age is not correlated with altered TNF-α gene expression in the skin punch biopsy samples obtained from the lateral lower leg of healthy controls (a, b) and PD patients (c, d). Abbreviations: PD = Parkinson’s disease, TNF-α = tumor necrosis factor-alpha.
Anastasia Kuzkina (14019707), Nurcan Üçeyler (226246), Susan Duty (9377420), Joana Lama (14019701), Elena Salabasidou (14019704), Jens Volkmann (295360)   +5 more
core   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Tumor nekrózis faktor-alfa (TNF-α) szerepe

, 2015
A TNF-α egy gyulladást keltő citokin, amelynek kettő formája ismert, egy szolubilis és egy membrán kötött. Részt vesznek a fertőzés és a daganatok elleni védekezésben, a sejtek túlélésének szabályozásában, illetve a homeosztázis fenntartásában is ...
Nemes, Olívia
core