Results 101 to 110 of about 182,358 (311)

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea, Boxer, Adam, Karydas, Anna, Kågedal, Katarina, Miller, Bruce, Rojas, Julio C, Seeley, William W, Svenningsson, Per, Svensson, Samuel   +8 more
core   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Studies of Single-Molecule Dynamics in Microorganisms [PDF]

, 2019
Fluorescence microscopy is one of the most extensively used techniques in the life sciences. Considering the non-invasive sample preparation, enabling live-cell compliant imaging, and the specific fluorescence labeling, allowing for a specific visualization
Turkowyd, Bartosz Daniel
core   +1 more source

Ductility Tuning via Cluster Network Characteristics of Porous Components

Advanced Materials Technologies, EarlyView.
Network optimization via cluster characteristics induced by interaction of stress concentration is proposed, demonstrating increased cluster size and dispersion in non‐uniform porous components. The optimized structures exhibit, for the first time, that enhanced ductility and damage progression is controllable through zigzag cluster network designed by
Ryota Toyoba, Yuichi Otsuka, Ian J Davies, Naritoshi Aoyagi, Yukio Miyashita   +4 more
wiley   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

Identification and preliminary characterization of mouse Adam33

BMC Genetics, 2002
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely distributed among metazoan phyla.
Hyman Richard W, Kim Philip H, Azarani Arezou, Gunn Teresa M, Davis Ronald W, Barsh Gregory S   +5 more
doaj   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Relevance of A Disintegrin and Metalloproteinase Domain-Containing (ADAM)9 Protein Expression to Bladder Cancer Malignancy [PDF]

, 2022
Moriwaki, Michika, Le, Trang Thi Huynh, Sung, Shian Ying, Jotatsu, Yura, Yang, Youngmin, Hirata, Yuto, Ishii, Aya, Chiang, Yi Te, Chen, Kuan Chou, shigemura, katsumi, Fujisawa, Masato   +10 more
openalex   +3 more sources

Expression, Localization, and Processing of Chicken Sperm ADAM32L2 during the Acrosome Reaction: A Possible Function in the Sperm–Egg Interaction

The Journal of Poultry Science
Sperm–egg interactions involve a complex series of molecular events. Among these, the acrosome reaction (AR) is a prerequisite for sperm penetration, facilitating the exposure of multiple acrosomal proteins that enhance sperm binding or penetration of ...
Mohamad Shuib Bin Mohamad Mohtar, Rangga Setiawan, Maiko Kuwabara, Atsushi Asano   +3 more
doaj   +1 more source

A Disintegrin and Metalloprotease (ADAM): Historical Overview of Their Functions

Toxins, 2016
Since the discovery of the first disintegrin protein from snake venom and the following identification of a mammalian membrane-anchored metalloprotease-disintegrin implicated in fertilization, almost three decades of studies have identified additional ...
Nives Giebeler, Paola Zigrino
doaj   +1 more source