Results 141 to 150 of about 171,066 (327)

Microvascular obstruction in cardiac amyloidosis

European Journal of Heart Failure, EarlyView.
Abstract Aims Cardiac amyloidosis (CA) is characterized by deposition of amyloid fibrils within the extracellular space, causing disarray of the myocardial structure and capillary architecture. This study aims to characterize the prevalence of microvascular obstruction (MVO) in patients with CA and to assess the association between MVO and prognosis ...
Lucrezia Netti, Adam Ioannou, Ana Martinez‐Naharro, Yousuf Razvi, Aldostefano Porcari, Lucia Venneri, Viviana Maestrini, Dan Knight, Ruta Virsinskaite, Muhammad U. Rauf, Tushar Kotecha, Rishi K. Patel, Ashutosh Wechelakar, Helen Lachmann, Peter Kellman, Charlotte Manisty, James Moon, Philip N. Hawkins, Julian D. Gillmore, Marianna Fontana   +19 more
wiley   +1 more source

Review on Synthesis Methods of Carbon Nanotubes as Activated Carbon Composites Based on Biomass for Supercapacitors in Electric Vehicles

Energy Technology, EarlyView.
This work reviews various methods to synthesize carbon nanotubes and analyzes the best methods to produce composites for supercapacitors for electric vehicles. Chemical vapor deposition is found to be the best method because the produced CNTs can be used directly without purification unless the catalyst particles need to be removed.
Apri Wiyono, Nurin Wahidah Mohd Zulkifli, Wan Mohd Ashri Wan Daud, Yusep Sukrawan, Rani Anggrainy, Ade Syafrinaldy, Henry Nolandy, Asroful Abidin, Ragil Sukarno, Muhammad Aziz   +9 more
wiley   +1 more source

CRISPR/Cas9‐mediated genome editing reveals seven testis‐enriched transmembrane glycoproteins dispensable for male fertility in mice

Andrology, EarlyView., 2023
Abstract Background Mammalian fertilization is mediated by multiple sperm acrosomal proteins, many of which are testis‐enriched transmembrane glycoproteins expressed during spermiogenesis (e.g., Izumo sperm‐egg fusion 1, Sperm acrosome associated 6, and Transmembrane protein 95).
Yo Ogawa, Yonggang Lu, Daiji Kiyozumi, Hsin‐Yi Chang, Masahito Ikawa   +4 more
wiley   +1 more source

Infrared‐Treated Diced Dehydrated Onion: Microbiological Shelf Life and Quality Changes

Food Safety and Health, EarlyView.
Blanched, dehydrated, and infrared‐treated diced onions were stored at 25°C, 30°C, and 37°C under 75% humidity. Changes in microbial and quality attributes were studied during the microbiological storage period. ABSTRACT Onion dehydration has been associated with surface contamination.
S. Savitha, Snehasis Chakraborty, Bhaskar N. Thorat   +2 more
wiley   +1 more source

Gut microbiota‐derived butyric acid regulates calcific aortic valve disease pathogenesis by modulating GAPDH lactylation and butyrylation

iMeta, EarlyView.
Multi‐omics sequencing and correlation analysis identified the beneficial role of Faecalibacterium prausnitzii (F. prausnitzii)‐derived butyric acid (BA) as a key metabolite in the restoration of valve function in calcific aortic valve disease (CAVD). The therapeutic efficacy of BA in attenuating CAVD progression was confirmed in vitro, ex vivo, and in
Chunli Wang, Zongtao Liu, Tingwen Zhou, Jiaqin Wu, Fan Feng, Shunshun Wang, Qingjia Chi, Yongqiang Sha, Shuai Zha, Songren Shu, Linghang Qu, Qianqian Du, Huiming Yu, Li Yang, Anna Malashicheva, Nianguo Dong, Fei Xie, Guixue Wang, Kang Xu   +18 more
wiley   +1 more source

A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm–Egg Plasma Membrane Adhesion and Fusion [PDF]

, 1997
Ruiyong Yuan, Paul Primakoff, Diana G. Myles   +2 more
openalex   +1 more source

Toward Informative Representations of Blood‐Based Infrared Spectra via Unsupervised Deep Learning

Journal of Biophotonics, EarlyView.
This study employs an unsupervised deep learning approach using a denoising autoencoder to distill blood‐based FTIR spectra into latent variables. By reducing noise and preserving essential information, the method enhanced lung cancer detection accuracy by 2.6%, providing a concise, clinically relevant representation of infrared spectra for improved ...
Corinna Wegner, Zita I. Zarandy, Nico Feiler, Lea Gigou, Timo Halenke, Niklas Leopold‐Kerschbaumer, Maik Krusche, Weronika Skibicka, Kosmas V. Kepesidis   +8 more
wiley   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules, Yukio Otsuka, Jace C. Nielsen, Megumi Iwai, Peter L. Bonate   +4 more
wiley   +1 more source

ADAM-10 Protein Is Present in Human Articular Cartilage Primarily in the Membrane-bound Form and Is Upregulated in Osteoarthritis and in Response to IL-1α in Bovine Nasal Cartilage [PDF]

, 2001
Susan Chubinskaya, Rita Mikhail, Angela J. Deutsch, M H Tindal   +3 more
openalex   +1 more source

Autoencoding Raman Spectra to Predict Analyte Concentrations

Journal of Raman Spectroscopy, EarlyView.
An autoencoder‐based machine learning regression model was developed using datasets from nuclear and biopharmaceutical industries, utilising spatial heterodyne spectrometers under spontaneous and resonance conditions. This study focuses on the impact of small data volumes on data augmentation and architecture designs.
Alex Poppe, Charles Warren, William Brooks, Stuart Gibson, Michael Foster   +4 more
wiley   +1 more source