Results 151 to 160 of about 20,502 (253)

Recombinant ADAMTS13 normalizes von Willebrand factor‐cleaving activity in plasma of acquired TTP patients by overriding inhibitory antibodies [PDF]

, 2011
Barbara Plaimauer, Johanna A. Kremer Hovinga, Claudia Juno, Martin J. Wolfsegger, Susanna Skalicky, Michaela Schmidt, Leopold Grillberger, Meinhard Hasslacher, Paul Knöbl, Hartmut J. Ehrlich, Friedrich Scheiflinger   +10 more
openalex   +1 more source

Effect of Caplacizumab in the Recovery of ADAMTS13 Level in Patients with Autoimmune Thrombotic Thrombocytopenic Purpura. Analysis from the Spanish Registry (REPTT) [PDF]

, 2023
María Eva Mingot‐Castellano, Cristina Izquierdo Pascual, Faustino García‐Candel, Jorge Martínez Nieto, José García-Arroba Peinado, Javier de la Rubia, Inés Gómez Seguí, Maria Liz Pacielo Coronel, David Valcárcel, Moraima Jiménez, Joan Cid, Miquel Lozano, José María García‐Gala, Sonia Angos Vazquez, Míriam Vara, Luisa Guerra, Francisca Avila Idrobo, ANA Yurena Oliva Hernandez, Saoia Zalba, Inmaculada Tallon Ruiz, Sandra Ortega Sánchez, Rosa Goterris, Maria Moreno Jimenez, Lourdes Dominguez Acosta, Maria Arraiz Ramirez, Luis M. Hernández, Elena Flores Ballesteros, Julio del Río-Garma   +27 more
openalex   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
,, Goodship, Tim H J, Machin, Sam, Taylor, C Mark, Wigmore, Stephen J   +4 more
core   +1 more source

GC1126A, a novel ADAMTS13 mutein, evades autoantibodies in immune-mediated thrombotic thrombocytopenic purpura

Scientific Reports
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare and life-threatening blood disorder characterized by the formation of blood clots in small blood vessels. It is caused by antibodies targeting the A disintegrin and metalloprotease with
Heechun Kwak, Gahee Choi, Suyong Kim, Ji-Min Park, Youngeun Kwon, Yongmin Lee, Chaemok Lee, Shangbin Yang, Spero Cataland, Sunghyun Kim, Soo-Mee Bang, Jae-Ho Yoon, Wooin Lee, Hyun-Ja Nam   +13 more
doaj   +1 more source

Keeping von Willebrand Factor under Control: Alternatives for ADAMTS13 [PDF]

, 2015
Claudia Tersteeg, Rob Fijnheer, Gerard Pasterkamp, Philip de Groot, Karen Vanhoorelbeke, Steven de Maat, Coen Maas   +6 more
openalex   +1 more source

ADAMTS13 regulates angiogenic markers via Ephrin/Eph signaling in human mesenchymal stem cells under serum-deprivation stress

Scientific Reports
Mesenchymal stem cells (MSCs) are known to facilitate angiogenesis and promote neo-vascularization via secretion of trophic factors. Here, we explored the molecular mechanism adopted by ADAMTS13 in modulating the expression of some key angiogenic markers
Srishti Dutta Gupta, Malancha Ta
doaj   +1 more source

N-Glycans of ADAMTS13 modulate its secretion and von Willebrand factor cleaving activity [PDF]

, 2008
Wenhua Zhou, Han‐Mou Tsai
openalex   +1 more source

Integrative Multi-omics Profiling Reveals CARMIL2/APBB1/ADAMTS13 as Immune-Related Hub Genes Governing Radiotherapy Response and Prognosis in Pancreatic Cancer [PDF]

J Tong, Di Chen, Wenjuan Chen, Yueting Han, F. R. Zeng, Liang Chen, Cheng-Yi Huang, Yangyang Gong, Huojun Zhang   +8 more
openalex   +1 more source

Systemic antithrombotic effects of ADAMTS13 [PDF]

, 2006
Anil K. Chauhan, David G. Motto, Colin B. Lamb, Wolfgang Bergmeier, Michael Dockal, Barbara Plaimauer, Friedrich Scheiflinger, David Ginsburg, Denisa D. Wagner   +8 more
openalex   +1 more source

ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria. [PDF]

A deficiency in ADAMTS13 (a von Willebrand factor [VWF] cleaving protease) is associated with accumulation of prothrombogenic unusually large VWF multimers (UL-VWF) in plasma. We studied VWF release and proteolysis in patients with symptomatic Plasmodium
Syafruddin D
core