Results 71 to 80 of about 2,929,035 (154)

Electroacupuncture Modulates Multiple Pathways for Neuroprotection and Neurorepair in Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
EA exerts therapeutic effects in ischemic stroke through multiple mechanisms: it alleviates acute injury by suppressing neuroinflammation, excitotoxicity, oxidative stress, apoptosis, pyroptosis, ferroptosis, autophagy dysregulation, and blood–brain barrier disruption, while enhancing cerebral blood flow, angiogenesis, and neurogenesis to support ...
Mingyue Zhao, Hangyu Shen, Xu Yan, Xiang Gao, Yuchun Liu, Shengjun Zhou, Jingxian Sun, Jie Sun, Yi Huang   +8 more
wiley   +1 more source

Mechanistic insights of sexual transmission of MPXV Clade I and II and associated impacts on the reproductive tissues: An integrated transcriptomic approach

In Silico Research in Biomedicine
Problem: Monkeypox virus (MPXV) has recently been detected in semen and genital secretions, raising the possibility of increased sexual transmission.
Shrabonti Chatterjee, Joydeep Mahata, Rakesh Kundu, Suprabhat Mukherjee, Mahasweta Nandi   +4 more
doaj   +1 more source

haemoreologic aspects of regulation of expression of angiogenesis modulating factors ADAMTS1, Angiopoietin-2 and Interleukin-8

, 2013
Ziel dieser Arbeit war die Untersuchung der strömungsabhängigen Expressionsregulation des antiangiogenen Faktors ADAMTS1 und des angiogenen Faktors Angiopoietin-2 in Endothelzellen in vitro und in vivo.
Hohberg, Margret
core   +1 more source

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome [PDF]

, 2017
Heritable thoracic aortic aneurysms and dissections (TAAD), including Marfan syndrome (MFS), currently lack a cure, and causative mutations have been identified for only a fraction of affected families.
Canelas, Lizet I, Renard, Marjolijn, Lozano-Vidal, Noelia, Milewicz, Dianna, Ruiz, E. Josue, Canelas, Lizet I., Ana M Briones, Hurlé, María A, Briones, Ana M, Redondo, Juan Miguel, Briones, Ana M., Ruiz, E Josue, De Backer, Julie, J Francisco Nistal, Oller, Jorge, Hurlé, María A., Noelia Lozano-Vidal, Mercedes Salaices, Silvia Villahoz, Rut Alberca, Nistal, J Francisco, Lizet I Canelas, Evangelista, Arturo, Backer, Julie de, Salaices, Mercedes, Marjolijn Renard, Méndez-Barbero, Nerea, Nistal, J. Francisco, Jorge Oller, Dianna Milewicz, Jiménez-Borreguero, Luis J., Campanero, Miguel R, María A Hurlé, Miguel R Campanero, Villahoz, Silvia, Nerea Méndez-Barbero, Jiménez-Borreguero, Luis Jesús, Arturo Evangelista, E Josue Ruiz, Juan Miguel Redondo, Julie De Backer, Luis Jesús Jiménez-Borreguero, Alberca, Rut, Campanero, Miguel R.   +43 more
core   +1 more source

Gene Expression Alterations Associated With Resveratrol‐Induced Antiproliferative Effects and S‐Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Osteosarcoma (OS) is an aggressive primary bone tumour with high metastatic potential. Current treatments including surgery and chemotherapy are limited by side effects and chemoresistance, underscoring the need for novel therapies. This study aimed to investigate the antitumor potential of resveratrol (RSV), a natural polyphenol, as a novel ...
Raffaella De Pace, Maria Rosa Iaquinta, Roberta Chiarelli, Maria Giulia Dell'Aquila, Fabio Casciano, Cinzia Brenna, Elisa Mazzoni   +6 more
wiley   +1 more source

Brevican abundance and proteolytic processing in ADAMTS1 null and wildtype frontal cortex extracts.

, 2012
(A) Representative immunoblots from female (F) and male (M) P8 and P28 ADAMTS1 null (−/−) and wildtype (+/+) frontal cortex protein extracts which show brevican (>145 kD, 145 kD, and 55 kD), the 55 kD ADAMTS-derived brevican fragment (EAMESE), the 53 kD ...
Paul E. Gottschall (127394), Antoni X. Torres-Collado (127386), Matthew D. Howell (127383), M. Luisa Iruela-Arispe (127389)   +3 more
core   +1 more source

Synaptic protein levels in P8, P28, and P90 ADAMTS1 null and wildtype frontal cortex extracts.

, 2012
The synaptic proteins (A and B) SNAP-25, (C and D) synaptophysin, and (E and F) PSD-95 were measured in frontal cortex protein extracts from female and male ADAMTS1 null (−/−) and wildtype (+/+) mice at P8, P28, and P90 (n = 4–7 per age, sex, and ...
Paul E. Gottschall (127394), Antoni X. Torres-Collado (127386), Matthew D. Howell (127383), M. Luisa Iruela-Arispe (127389)   +3 more
core   +1 more source

ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors [PDF]

, 2010
Background Decreased expression of the angiogenesis inhibitor ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1) has previously been reported during prostate cancer progression.
Jennbacken Karin, Gustavsson Heléne, Tajana Tešan, Heléne Gustavsson, Jan-Erik Damber, Tešan Tajana, Kouji Kuno, Damber Jan-Erik, Kuno Kouji, Welén Karin, Karin Jennbacken, Karin Welén   +11 more
core   +1 more source

Electroacupuncture promotes angiogenesis by regulating miR-142-5p and activating ADAMTS1/PI3K/AKT pathway in ischemic stroke rats

针刺研究
ObjectiveTo observe the effect of electroacupuncture on miR-142-5p and ADAMTS1/PI3K/AKT pathway in rats with ischemic stroke， so as to explore the regulatory mechanism of electroacupuncture on angiogenesis after ischemic stroke.MethodsThis study was ...
SI Shu-han, SONG Shi-zhen, XIE Xue-yun, ZHANG Ting-ting, KUI Xiao-fei, YANG Xiao-hui, ZHOU Shuang   +6 more
doaj  

Increase of ADAMTS1 mRNA correlated with reduction of ADAMTS1 promoter-associated H3K27me3 and EZH2 binding through passages.

, 2012
(A) ADAMTS1 mRNA levels in indicated NAF derivatives were analyzed and shown gradually increased in NAF 200N.E4 from P0 to P3 and maintained from P3 to P5. (B) MeDIP indicates that ADAMTS1 promoter-associated DNA methylation level was similar in NAF 200N.
Li-Jung Juan (171247), Chih-Hung Hsu (171225), Kai-Lin Peng (171228), Jin-Yuh Shew (171239), Eva Y.-H. P. Lee (171236), King-Jen Chang (132031), Wen-Hwa Lee (171250), Wen-Hung Kuo (132019), Chun-Chin Chen (171232), Shiaw-Wei Tyan (171220)   +9 more
core   +1 more source