Results 61 to 70 of about 458,251 (312)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Aquaculture Ecosystems: Adaptability and Sustainability [PDF]

open access: yes, 2015
The book focuses on incorporating elements of adaptability and sustainability in aquaculture with a view to changing the course of development of the aquaculture industry towards an ecosystem approach.

core   +1 more source

Raw aquaculture wastewater treatment using microalgal monocultures, a co-culture, and a microalgae-bacteria consortium within a revolving algal biofilm (RAB) system

open access: yesChemical Engineering Journal Advances
Microalgae-based technology is an environmentally friendly and cost-effective method for wastewater treatment. This study investigated the microalgal biofilm formation and nutrient removal in a revolving algal biofilm (RAB) system for treating raw ...
Lin-Yun Liao   +6 more
doaj   +1 more source

Increasing Environmental Complexity by Providing Different Types of Litter and Perches during Early Rearing Boosts Coping Abilities in Domestic Fowl Chicks

open access: yesAnimals, 2022
Early experience of a complex environment can improve biologically relevant traits related to coping abilities. However, the mechanisms underlying these positive effects have not been well explored.
Franco Nicolas Nazar   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Diurnal Variation in Transport and Use of Intracellular Leaf Water and Related Photosynthesis in Three Karst Plants

open access: yesAgronomy, 2022
Except for transpired water, the intracellular water stored in leaves accounts for only 1–3% of the water absorbed by roots. Understanding water transport and use, as well as the related photosynthetic response, helps with determining plant water status ...
Xiaojie Qin   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The perspectives of the use of Flexbox technology at adaptive creation of the web pages

open access: yesТехнічна інженерія, 2019
The correct creation of the site is responsible for the correct display of the content. The developer must create web-page, that will be displayed correctly in the browser, which will be the closest to the previously created layout design site, pre ...
V.V. Bolotina   +2 more
doaj   +1 more source

Improving the Robustness of Online Social Networks: A Simulation Approach of Network Interventions

open access: yesFrontiers in Robotics and AI, 2020
Online social networks (OSN) are prime examples of socio-technical systems in which individuals interact via a technical platform. OSN are very volatile because users enter and exit and frequently change their interactions.
Giona Casiraghi, Frank Schweitzer
doaj   +1 more source

Effect of the Altitude Gradient on the Physiological Performance of Quinoa in the Central Region of Colombia

open access: yesAgronomy, 2022
The conditions of the agroecological environment play a fundamental role in the physiological performance of quinoa; however, due to the accelerated expansion of quinoa cultivation and the great diversity of cultivars present in the world, it has not ...
Miguel García-Parra   +2 more
doaj   +1 more source

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