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Distinguishing Biological Trends from Adaptation
Philosophy, Theory, and Practice in Biology, 2022 Models of evolution commonly decompose change into deterministic and stochastic components. Different models, however, produce different concepts of signal and noise.
Lucas John Mix
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Stem Cell Research, 2023 A number of genetic variants in the SYNM gene encoding for the intermediate filament synemin have been reported in patients with cardiomyopathies, skeletal myopathies, cancer and certain neurodegenerative disorders.
Caterina Gargano +7 more
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Discovering adaptation-capable biological network structures using control-theoretic approaches
PLoS Comput. Biol., 2022 Constructing biological networks capable of performing specific biological functionalities has been of sustained interest in synthetic biology. Adaptation is one such ubiquitous functional property, which enables every living organism to sense a change ...
Priyan Bhattacharya +2 more
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Cells, 2021 Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and universal system for protecting cells and the whole body from various types of stress.
Olga G. Zatsepina +2 more
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Computational Probing the Methylation Sites Related to EGFR Inhibitor-Responsive Genes
Biomolecules, 2021 The emergence of drug resistance is one of the main obstacles to the treatment of lung cancer patients with EGFR inhibitors. Here, to further understand the mechanism of EGFR inhibitors in lung cancer and offer novel therapeutic targets for anti-EGFR ...
Rui Yuan, Shilong Chen, Yongcui Wang
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Modeling adaptive biological systems [PDF]
Biosystems, 1989 During the evolution of many systems found in nature, both the system composition and the interactions between components will vary. Equating the dimension with the number of different components, a system which adds or deletes components belongs to a class of dynamical systems with a finite dimensional phase space of variable dimension. We present two
Bagley, R. J. +5 more
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Frontiers in Bioengineering and Biotechnology, 2022 As part of applications dealing with cardiovascular tissue engineering, drop-cast polyvinylidene fluoride (PVDF) scaffolds have been treated by cold plasma to enhance their adherence to cardiac cells.
Maria Kitsara +9 more
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Absence of Desmin Results in Impaired Adaptive Response to Mechanical Overloading of Skeletal Muscle
Frontiers in Cell and Developmental Biology, 2021 Background: Desmin is a muscle-specific protein belonging to the intermediate filament family. Desmin mutations are linked to skeletal muscle defects, including inherited myopathies with severe clinical manifestations.
Pierre Joanne +12 more
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Biological Impacts of Marine Heatwaves.
Annual Review of Marine Science, 2022 Climatic extremes are becoming increasingly common against a background trend of global warming. In the oceans, marine heatwaves (MHWs)-discrete periods of anomalously warm water-have intensified and become more frequent over the past century, impacting ...
Kathryn E. L. Smith +8 more
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Nitrite Oxidation in Wastewater Treatment: Microbial Adaptation and Suppression Challenges
Environmental Science and Technology, 2023 Microbial nitrite oxidation is the primary pathway that generates nitrate in wastewater treatment systems and can be performed by a variety of microbes: namely, nitrite-oxidizing bacteria (NOB).
Zicheng Su +3 more
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