Results 11 to 20 of about 405,074 (267)

Climate change and the global redistribution of biodiversity: substantial variation in empirical support for expected range shifts

Environmental Evidence, 2023
Background Among the most widely predicted climate change-related impacts to biodiversity are geographic range shifts, whereby species shift their spatial distribution to track their climate niches.
Madeleine A. Rubenstein, Sarah R. Weiskopf, Romain Bertrand, Shawn L. Carter, Lise Comte, Mitchell J. Eaton, Ciara G. Johnson, Jonathan Lenoir, Abigail J. Lynch, Brian W. Miller, Toni Lyn Morelli, Mari Angel Rodriguez, Adam Terando, Laura M. Thompson   +13 more
doaj   +1 more source

Slug, a Cancer‐Related Transcription Factor, is Involved in Vascular Smooth Muscle Cell Transdifferentiation Induced by Platelet‐Derived Growth Factor‐BB During Atherosclerosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Heart attacks and stroke often result from occlusive thrombi following the rupture of vulnerable atherosclerotic plaques. Vascular smooth muscle cells (VSMCs) play a pivotal role in plaque vulnerability because of their switch towards a ...
Nahéma Ledard, Alexandrine Liboz, Bertrand Blondeau, Mégane Babiak, Célia Moulin, Benjamin Vallin, Isabelle Guillas, Véronique Mateo, Claire Jumeau, Karl Blirando, Olivier Meilhac, Isabelle Limon, Martine Glorian   +12 more
doaj   +1 more source

Tradeoffs in adapting biological systems

European Journal of Control, 2016
Biological systems must sense and adapt to changes in their environment. Molecular networks capable of such adaptation belong to two well-known classes, feed-forward and feedback structures, but the fundamental limitations and tradeoffs of these two classes remain unknown.
Rajat Bhatnagar, Hana El-Samad
openaire   +4 more sources

Symmetry Invariance for Adapting Biological Systems [PDF]

SIAM Journal on Applied Dynamical Systems, 2011
We study in this paper certain properties of the responses of dynamical systems to external inputs. The motivation arises from molecular systems biology. and, in particular, the recent discovery of an important transient property, related to Weber's law in psychophysics: "fold-change detection" in adapting systems, the property that scale uncertainty ...
Oren Shoval, Uri Alon 0001, Eduardo D. Sontag   +2 more
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The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function

Antioxidants, 2018
Cysteine and methionine residues are the amino acids most sensitive to oxidation by reactive oxygen species. However, in contrast to other amino acids, certain cysteine and methionine oxidation products can be reduced within proteins by dedicated ...
Sofia Lourenço dos Santos, Isabelle Petropoulos, Bertrand Friguet   +2 more
doaj   +1 more source

Vimentin as a target for the treatment of COVID-19

BMJ Open Respiratory Research, 2020
We and others propose vimentin as a possible cellular target for the treatment of COVID-19. This innovative idea is so recent that it requires further attention and debate.
Zhenlin Li, Denise Paulin, Patrick Lacolley, Dario Coletti, Onnik Agbulut   +4 more
doaj   +1 more source

THE BIOLOGICAL PROBLEM OF ADAPTATION [PDF]

The Journal OF Nervous and Mental Disease, 1920
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Mimetismo molecular e interacciones entre la glicoproteína S de SARS-CoV-2 y proteínas humanas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2021
Fundamento: el mimetismo entre la glicoproteína S de SARS-CoV-2 y moléculas humanas puede ser parte de los mecanismos implicados en las afectaciones causadas por el virus en órganos dianaObjetivo: identificar, con el empleo de herramientas ...
Kendria Beatriz Góngora-Parra, Nataly Rodríguez-González, Orlando Rafael Serrano-Barrera   +2 more
doaj  

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

Redox Biology, 2015
IL-1β production is critically regulated by cytosolic molecular complexes, termed inflammasomes. Different inflammasome complexes have been described to date.
Amna Abderrazak, Tatiana Syrovets, Dominique Couchie, Khadija El Hadri, Bertrand Friguet, Thomas Simmet, Mustapha Rouis   +6 more
doaj   +1 more source

Vulnerability of Estuarine Systems in the Contiguous United States to Water Quality Change Under Future Climate and Land‐Use

Earth's Future, 2023
Changes in climate and land‐use and land‐cover (LULC) are expected to influence surface water runoff and nutrient characteristics of estuarine watersheds, but the extent to which estuaries are vulnerable to altered nutrient loading under future ...
L. R. Montefiore, N. G. Nelson, M. D. Staudinger, A. Terando   +3 more
doaj   +1 more source