Results 21 to 30 of about 434,212 (312)

Vimentin as a target for the treatment of COVID-19

open access: yesBMJ Open Respiratory Research, 2020
We and others propose vimentin as a possible cellular target for the treatment of COVID-19. This innovative idea is so recent that it requires further attention and debate.
Zhenlin Li   +4 more
doaj   +1 more source

THE BIOLOGICAL PROBLEM OF ADAPTATION [PDF]

open access: yesThe Journal OF Nervous and Mental Disease, 1920
n ...
openaire   +2 more sources

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

open access: yesRedox Biology, 2015
IL-1β production is critically regulated by cytosolic molecular complexes, termed inflammasomes. Different inflammasome complexes have been described to date.
Amna Abderrazak   +6 more
doaj   +1 more source

Vulnerability of Estuarine Systems in the Contiguous United States to Water Quality Change Under Future Climate and Land‐Use

open access: yesEarth's Future, 2023
Changes in climate and land‐use and land‐cover (LULC) are expected to influence surface water runoff and nutrient characteristics of estuarine watersheds, but the extent to which estuaries are vulnerable to altered nutrient loading under future ...
L. R. Montefiore   +3 more
doaj   +1 more source

Climate Variability and Change Affect Crops Yield under Rainfed Conditions: A Case Study in Gedaref State, Sudan

open access: yesAgronomy, 2021
It is projected that, on average, annual temperature will increase between 2 °C to 6 °C under high emission scenarios by the end of the 21st century, with serious consequences in food and nutrition security, especially within semi-arid regions of sub ...
Maysoon A. A. Osman   +4 more
doaj   +1 more source

Evolutionary adaptability of biological macromolecules [PDF]

open access: yesJournal of Molecular Evolution, 1977
The degree of gradualism with which tertiary structure and function of protein changes with stepwise changes in primary structure (assumed to be influenced by redundancy of weak bonding) is both a precondition for and consequence of evolution. The resulting selection for degree of gradualism has implications for a number of structural and functional ...
openaire   +3 more sources

The time course of adaptation to spatial contrast [PDF]

open access: yes, 1991
We explored the buildup and decay of threshold elevation during and after adaptation to sinewave gratings in a series of experiments investigating the effects of adapting time, adapting contrast, spatial frequency and retinal eccentricity.
Harris, J. P.   +3 more
core   +1 more source

An adaptive microscope for the imaging of biological surfaces [PDF]

open access: yesLight: Science & Applications, 2021
AbstractScanning fluorescence microscopes are now able to image large biological samples at high spatial and temporal resolution. This comes at the expense of an increased light dose which is detrimental to fluorophore stability and cell physiology.
Abouakil, Faris   +5 more
openaire   +4 more sources

When adaptation is slowed down: Genomic analysis of evolutionary stasis in thermal tolerance during biological invasion in a novel climate

open access: yes, 2023
Research conducted during the past two decades has demonstrated that biological invasions are excellent models of rapid evolution. Even so, characteristics of invasive populations such as a short time for recombination to assemble optimal combinations of
Kolbe, Jason J   +10 more
core   +1 more source

Rbm24 displays dynamic functions required for myogenic differentiation during muscle regeneration

open access: yesScientific Reports, 2021
Skeletal muscle has a remarkable capacity of regeneration after injury, but the regulatory network underlying this repair process remains elusive. RNA-binding proteins play key roles in the post-transcriptional regulation of gene expression and the ...
Raphaëlle Grifone   +7 more
doaj   +1 more source

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