Results 31 to 40 of about 405,074 (267)

MiRroring the Multiple Potentials of MicroRNAs in Acute Myocardial Infarction

Frontiers in Cardiovascular Medicine, 2017
At present, cardiovascular diseases are depicted to be the leading cause of death worldwide according to the World Health Organization. In the future, projections predict that ischemic heart disease will persist in the top main causes of illness.
Solenne Paiva, Onnik Agbulut
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Restrictions on biological adaptation in language evolution [PDF]

Proceedings of the National Academy of Sciences, 2009
Language acquisition and processing are governed by genetic constraints. A crucial unresolved question is how far these genetic constraints have coevolved with language, perhaps resulting in a highly specialized and species-specific language “module,” and how much language acquisition and processing redeploy preexisting cognitive machinery.
Nick, Chater, Florencia, Reali, Morten H, Christiansen   +2 more
openaire   +2 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Genetic analysis identifies key loci for traits and resistance in Qinghai plateau wheat F2 populations

Scientific Reports
The Qinghai Plateau’s high-altitude conditions present significant challenges for wheat cultivation, demanding varieties with enhanced adaptability and stress resistance.
Demei Liu, Ahmed H. El-Sappah, Ahmed S. Eldomiaty, Haiqing Wang, Wenjie Chen, Ruijuan Liu, Jicheng Shen, Fahui Ye   +7 more
doaj   +1 more source

Mobile phone data reveals spatiotemporal recreational patterns in conservation areas during the COVID pandemic

Scientific Reports, 2023
Understanding visitation patterns is crucial in developing effective conservation strategies for protected areas, as it serves as an indicator for operating an ecosystem management plan that balances biodiversity and ecosystem services intertwined with ...
Ji Yoon Kim, Takahiro Kubo, Jun Nishihiro   +2 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Scaffolding Protein GspB/OutB Facilitates Assembly of the Dickeya dadantii Type 2 Secretion System by Anchoring the Outer Membrane Secretin Pore to the Inner Membrane and to the Peptidoglycan Cell Wall

mBio, 2022
The phytopathogenic proteobacterium Dickeya dadantii secretes an array of plant cell wall-degrading enzymes and other virulence factors via the type 2 secretion system (T2SS).
Shiheng Zhang, Shuang Gu, Piers Rycroft, Florence Ruaudel, Frederic Delolme, Xavier Robert, Lionel Ballut, Richard W. Pickersgill, Vladimir E. Shevchik   +8 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

An Adaptation of Bicgstab for Nonlinear Biological Systems [PDF]

, 2006
Here we propose a new adaptation of Van der Vorst’s BiCGStab to nonlinear systems, a method combining the iterative features of both sparse linear system solvers, such as BiCGStab, and of nonlinear systems, which in general are linearized by forming Jacobians, and whose resulting system usually involves the use of a linear solver.
Ezio Venturino, Peter R. Graves-Morris, Alessandra De Rossi   +2 more
openaire   +1 more source