Results 51 to 60 of about 405,074 (267)
Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
Stem Cell Research & TherapyBackground Beyond the observed alterations in cellular structure and mitochondria, the mechanisms linking rare genetic mutations to the development of heart failure in patients affected by desmin mutations remain unclear due in part, to the lack of ...
Yeranuhi Hovhannisyan +21 more
doaj +1 more source
Toxins, 2022 Two recently revised Azemiops snakes with apparent differences in their external appearances and skeletal morphologies but unclear genetic boundaries have been proposed. Some researchers have refrained from using the newly proposed taxonomy because these
Si-Rui Zheng +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
BMC Evolutionary Biology, 2017 Background Polyploidy plays an important role in the adaptation and speciation of plants. The alteration of karyotype is a significant event during polyploidy formation. The Medicago sativa complex includes both diploid (2n = 2× = 16) and tetraploid (2n =
Feng Yu +6 more
doaj +1 more source
Is Storytelling a Biological Adaptation? [PDF]
, 2012 Verbal storytelling – in a sense broad enough to include all forms from casual conversation across oral folklore to written literature – seems to be a universal human activity and has thus been considered an evolutionary adaptation several times in the past few years.
openaire +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
BMC Public Health, 2018 Background The decline in global malaria cases is attributed to intensified utilization of primary vector control interventions and artemisinin-based combination therapies (ACTs). These strategies are inadequate in many rural areas, thus adopting locally
Jacinter A. Amadi +5 more
doaj +1 more source
An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Completing and Adapting Models of Biological Processes [PDF]
, 2006 We present a learning-based method for model completion and adaptation, which is based on the combination of two approaches: 1) R2D2C, a technique for mechanically transforming system requirements via provably equivalent models to running code, and 2) automata learning-based model extrapolation.
Tiziana Margaria +5 more
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