Results 21 to 30 of about 5,385,083 (246)

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

open access: yesRedox Biology, 2015
IL-1β production is critically regulated by cytosolic molecular complexes, termed inflammasomes. Different inflammasome complexes have been described to date.
Amna Abderrazak   +6 more
doaj   +1 more source

Climate Variability and Change Affect Crops Yield under Rainfed Conditions: A Case Study in Gedaref State, Sudan

open access: yesAgronomy, 2021
It is projected that, on average, annual temperature will increase between 2 °C to 6 °C under high emission scenarios by the end of the 21st century, with serious consequences in food and nutrition security, especially within semi-arid regions of sub ...
Maysoon A. A. Osman   +4 more
doaj   +1 more source

An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue [PDF]

open access: yes, 2011
Evolutionary processes in biological tissue, such as adaptation or remodeling, represent an enterprising area of research. In this paper, we present a multiscale model for the remodeling of fibered structures, such as bundles of collagen fibrils.
Doblaré, Manuel   +3 more
core   +2 more sources

Vulnerability of Estuarine Systems in the Contiguous United States to Water Quality Change Under Future Climate and Land‐Use

open access: yesEarth's Future, 2023
Changes in climate and land‐use and land‐cover (LULC) are expected to influence surface water runoff and nutrient characteristics of estuarine watersheds, but the extent to which estuaries are vulnerable to altered nutrient loading under future ...
L. R. Montefiore   +3 more
doaj   +1 more source

Symmetry Invariance for Adapting Biological Systems [PDF]

open access: yesSIAM Journal on Applied Dynamical Systems, 2011
We study in this paper certain properties of the responses of dynamical systems to external inputs. The motivation arises from molecular systems biology. and, in particular, the recent discovery of an important transient property, related to Weber's law in psychophysics: "fold-change detection" in adapting systems, the property that scale uncertainty ...
Shoval, Oren, Alon, Uri, Sontag, Eduardo
openaire   +2 more sources

Evolutionary adaptability of biological macromolecules [PDF]

open access: yesJournal of Molecular Evolution, 1977
The degree of gradualism with which tertiary structure and function of protein changes with stepwise changes in primary structure (assumed to be influenced by redundancy of weak bonding) is both a precondition for and consequence of evolution. The resulting selection for degree of gradualism has implications for a number of structural and functional ...
openaire   +3 more sources

Biological clockwork underlying adaptive rhythmic movements [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
Significance Animals can adapt the frequency and shape of their oscillatory body movements during locomotion in response to changes in the environment. Although central pattern generators (CPGs) are known to be the basic neuronal circuits responsible for generation of rhythmic movements, no conclusive evidence has so far been found to ...
Chen, Jun, Friesen, W, Iwasaki, Tetsuya
openaire   +6 more sources

Model Reduction on the Wnt Pathway Leads to Biological Adaptation [PDF]

open access: yes, 2001
Complex systems are an unavoidable problem in the field of biology. One of the ways that scientists have tried to overcome this problem is by building mathematical models—manageable representations designed to look at specific physical phenomena. The Wnt
Filej, B.   +4 more
core   +2 more sources

Tradeoffs in adapting biological systems

open access: yesEuropean Journal of Control, 2016
Biological systems must sense and adapt to changes in their environment. Molecular networks capable of such adaptation belong to two well-known classes, feed-forward and feedback structures, but the fundamental limitations and tradeoffs of these two classes remain unknown.
Bhatnagar, Rajat, El-Samad, Hana
openaire   +4 more sources

Dynamics of Coupled Adaptive Elements : Bursting and Intermittent Oscillations Generated by Frustration in Networks [PDF]

open access: yes, 2009
Adaptation to environmental change is a common property of biological systems. Cells initially respond to external changes in the environment, but after some time, they regain their original state.
A. P. Gasch   +11 more
core   +1 more source

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