Results 81 to 90 of about 1,206,348 (301)

Local adaptation of two cryptic species, Lasthenia californica and Lasthenia gracilis, to distinct regions within a serpentine outcrop [PDF]

, 2013
Intraspecific variation providing tolerance to specific edaphic conditions may contribute to population differentiation, speciation, and species coexistence.
Barry, Teri
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Generation of human induced pluripotent stem cell lines from five patients with Myofibrillar myopathy carrying different heterozygous mutations in the DES gene

Stem Cell Research
Myofibrillar myopathy (MFM) is a rare genetic disorder characterized by muscular dystrophy that is often associated with cardiac disease. This disease is caused by mutations in several genes, among them DES (encoding desmin) is the most frequently ...
Pierre Joanne, Yeranuhi Hovhannisyan, Alexandre Simon, Gaëlle Revet, Romain Diot, Gabriel Friob, Denisa Calin, Zhenlin Li, Anthony Béhin, Karim Wahbi, Gérard Tachdjian, Onnik Agbulut   +11 more
doaj   +1 more source

A genome‐wide investigation of the worldwide invader Sargassum muticum shows high success albeit (almost) no genetic diversity

Evolutionary Applications, 2020
Twenty years of genetic studies of marine invaders have shown that successful invaders are often characterized by native and introduced populations displaying similar levels of genetic diversity.
Sabrina Le Cam, Claire Daguin‐Thiébaut, Sarah Bouchemousse, Aschwin H. Engelen, Nova Mieszkowska, Frédérique Viard   +5 more
doaj   +1 more source

Invariant template matching in systems with spatiotemporal coding: a vote for instability

, 2007
We consider the design of a pattern recognition that matches templates to images, both of which are spatially sampled and encoded as temporal sequences. The image is subject to a combination of various perturbations.
Alonso, Amit, Amit, Amit, Attneave, Baccus, Banham, Blake, Bueso, Cees van Leeuwen, Demontis, Enroth-Cugell, Fradkov, Fuchs, Gabor, Gilden, Gorban, Guckenheimer, Gutig, Hansel, Hatfield, Herz, Hindmarsh, Hofer, Hopfield, Ivan Tyukin, Izhikevich, Jain, Kaneko, Kaneko, Khalil, Lachmann, Lee, Leeuwenberg, Leopold, Mather, Miller, Milnor, Mon-Williams, Pogromsky, Rabinovic, Ritter, Rodieck, Sharpe, Shepard, Smirnakis, Smith, Smith, Tatiana Tyukina, Tsuda, Tyukin, Tyukin, Ullman, van Leeuwen, van Leeuwen, Webster, Wolfson   +56 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Decreasing psychological distance to climate adaptation through serious gaming: Minions of Disruptions

Climate Services
A gap between knowledge and adaptive action remains and psychological distancing has been proposed to explain peoples’ inaction. This presents a challenge to climate change communication and particularly to the conventional ways of providing scientific ...
Minja Sillanpää, Julia Eichhorn, Sirkku Juhola   +2 more
doaj   +1 more source

Memory and information processing in neuromorphic systems

, 2015
A striking difference between brain-inspired neuromorphic processors and current von Neumann processors architectures is the way in which memory and processing is organized.
Indiveri, Giacomo, Liu, Shih-Chii
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Thioredoxin 2 protects mice against experimental myocardial infarction

Redox Experimental Medicine
Experimental Myocardial infarction (MI) using ligation procedure induces cardiac dysfunction, high level of ROS, inflammation, apoptosis, fibrosis and cardiomyocyte (CM) loss. AAV overexpressing human Trx-2, specifically in CM mitochondria improves mouse
Tania Medali, Dominique Couchie, Nathalie Mougenot, Maria Mihoc, Olaf Bergmann, Wouter Derks, Celio X Santos, Bertrand Friguet, Mustapha Rouis   +8 more
doaj   +1 more source