Results 51 to 60 of about 358,354 (313)

Physiological adaptation to altitude. Possible therapeutic implications [PDF]

open access: yes, 2020
25 p. : il. -- Bibliogr.: p. 24-25High altitude is characterised by hypoxia; low levels of oxygen in the atmosphere create a deficiency in oxygen reaching the tissues.
Macaya Alonso, Alicia
core   +2 more sources

The Influence Of Stimulus And Coping Mechanism To Hiv/Aids Patient Adaptation Based On Callista Roy Theory In Regional Public Hospital Kota Probolinggo

open access: yesJurnal Ners dan Kebidanan Indonesia, 2019
HIV/AIDS patients experienced various problems that reviewed of adaptation models such as physical, psychological, social and dependency problems. The adaptation process can be influenced by stimulus and coop mechanism, one of stimulus which appear to ...
Dodik Hartono   +2 more
doaj   +1 more source

Physiological Genomics of Temperature Adaptation among Natural Fundulus heteroclitus Populations

open access: yes, 2023
Adaptation acting on physiological processes may occur if temperature differences are consistent, and drift is low. Yet characterizing temperature adaptation is challenging and an integrative approach combining physiological, molecular, and genomic data ...
DeLiberto, Amanda
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Modeling flexible behavior with remapping-based hippocampal sequence learning

open access: yeseLife
Animals flexibly change their behavior depending on context. It is reported that the hippocampus is one of the most prominent regions for contextual behaviors, and its sequential activity shows context dependency.
Yoshiki Ito, Taro Toyoizumi
doaj   +1 more source

Anthropometric and Physiological Responses to Prolonged Open Water Rowing: A Case Study

open access: yes, 2003
The objective of the study was to examine the anthropometric and physiological responses to a prolonged period of open water rowing 4950 km. A single male (novice) rower underwent assessment of anthropometric variables, pre- and post-race, for the ...
Dan A. Gordon, Gordon, Dan A.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Physiological adaptation in savanna ungulates [PDF]

open access: yesProceedings of the Nutrition Society, 1997
Savannas lie between the equatorial rain forests and the semi-deserts of the southern continents. From the herbivore’s viewpoint, the savanna environment is characterized by a mixture of herbaceous and woody vegetation, varying in quantity and growth stage according to the seasonal cycle of rainfall. C4 grasses (i.e.
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy