Results 51 to 60 of about 358,354 (313)
Physiological adaptation to altitude. Possible therapeutic implications [PDF]
25 p. : il. -- Bibliogr.: p. 24-25High altitude is characterised by hypoxia; low levels of oxygen in the atmosphere create a deficiency in oxygen reaching the tissues.
Macaya Alonso, Alicia
core +2 more sources
HIV/AIDS patients experienced various problems that reviewed of adaptation models such as physical, psychological, social and dependency problems. The adaptation process can be influenced by stimulus and coop mechanism, one of stimulus which appear to ...
Dodik Hartono +2 more
doaj +1 more source
Physiological Genomics of Temperature Adaptation among Natural Fundulus heteroclitus Populations
Adaptation acting on physiological processes may occur if temperature differences are consistent, and drift is low. Yet characterizing temperature adaptation is challenging and an integrative approach combining physiological, molecular, and genomic data ...
DeLiberto, Amanda
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Modeling flexible behavior with remapping-based hippocampal sequence learning
Animals flexibly change their behavior depending on context. It is reported that the hippocampus is one of the most prominent regions for contextual behaviors, and its sequential activity shows context dependency.
Yoshiki Ito, Taro Toyoizumi
doaj +1 more source
Anthropometric and Physiological Responses to Prolonged Open Water Rowing: A Case Study
The objective of the study was to examine the anthropometric and physiological responses to a prolonged period of open water rowing 4950 km. A single male (novice) rower underwent assessment of anthropometric variables, pre- and post-race, for the ...
Dan A. Gordon, Gordon, Dan A.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Physiological adaptation in savanna ungulates [PDF]
Savannas lie between the equatorial rain forests and the semi-deserts of the southern continents. From the herbivore’s viewpoint, the savanna environment is characterized by a mixture of herbaceous and woody vegetation, varying in quantity and growth stage according to the seasonal cycle of rainfall. C4 grasses (i.e.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

