Results 51 to 60 of about 2,568,811 (261)
HIV/AIDS patients experienced various problems that reviewed of adaptation models such as physical, psychological, social and dependency problems. The adaptation process can be influenced by stimulus and coop mechanism, one of stimulus which appear to ...
Dodik Hartono +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Framing adaptation in the Victorian context: synthesis report [PDF]
This synthesis report provides a summary of the research activity and conveys the key findings arising from the 18 month ‘Framing Adaptation in the Victorian Context’ project undertaken between 2010 and 2012.
Hartmut Funfgeld, Darryn McEvoy
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Valuing adaptation under rapid change [PDF]
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young +2 more
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Effect of Contrast and Adaptation on the Perception of the Direction and Speed of Drifting Gratings [PDF]
Three experiments were conducted to analyse the effect of contrast and adaptation state on the ability of human observers to discriminate the motion of drifting gratings.
Müller, Rolf +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Climate change adaptation in the boardroom [PDF]
Climate adaptation is recognised by many of the world’s largest businesses as a global risk and one that requires critical attention. The World Economic Forum’s 2013 Global Risks Perception Survey, identified the ‘failure of climate change adaptation and
Mark Baker-Jones +2 more
core
Physiological Genomics of Temperature Adaptation among Natural Fundulus heteroclitus Populations
Adaptation acting on physiological processes may occur if temperature differences are consistent, and drift is low. Yet characterizing temperature adaptation is challenging and an integrative approach combining physiological, molecular, and genomic data ...
DeLiberto, Amanda
core +4 more sources

