Results 71 to 80 of about 362,441 (313)

Electrophysiological Heterogeneity of Fast-Spiking Interneurons: Chandelier versus Basket Cells [PDF]

open access: yes, 2013
In the prefrontal cortex, parvalbumin-positive inhibitory neurons play a prominent role in the neural circuitry that subserves working memory, and alterations in these neurons contribute to the pathophysiology of schizophrenia.
Povysheva, Nadezhda V.   +16 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Adaptation [PDF]

open access: yes, 2019
While adaptations to local environments are well recognized, their actual influence on the dynamics of organisms (e.g., demography of mortality, growth, and reproduction) at a population level are less studied.
Peter Biro (13088787)   +1 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Coupling Interaction and Physiological Metrics for Interaction Adaptation [PDF]

open access: yes, 2011
Part 1: Long and Short PapersInternational audienceWe present an adaptation system whose goal is to provide users with interaction experiences tailored to their current physiological status and performance.
Carriço, Luís   +3 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Livestock robustness: physiological and behavioural levers of adaptation [PDF]

open access: yes, 2023
International audienceIn Mediterranean and Tropical livestock production systems, animals are faced with sometimes drastic variations in the availability of food resources, for example duringmore or less predictable and extended droughts, leading to ...
González García, Eliel   +4 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Does performance during the ISWT truly reflect changes in physiological function? [PDF]

open access: yes, 2009
This aim of this dissertation is to evaluate whether changes in performance i.e. maximum distance walked (MDW) in the ISWT truly reflect improvements in physiological fitness in patients who have undergone a 3 month course of cardiac rehabilitation. (CR)
Innes, Geraldine
core  

Changes in Cortisol Awakening Response During 10 Days of High-Intensity Cycling Exercise

open access: yesLife
Previous studies suggest that the cortisol awakening response (CAR) shows a biphasic pattern—either an increase or a blunting—in response to exercise involving overload, potentially reflecting physiological adaptation. However, its response to continuous
Yui Ogasawara   +2 more
doaj   +1 more source

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