Results 71 to 80 of about 2,568,811 (261)

Role of Tau Protein in Both Physiological and Pathological Conditions [PDF]

, 2004
The morphology of a neuron is determined by its cytoskeletal scaffolding. Thus proteins that associate with the principal cytoskeletal components such as the microtubules have a strong influence on both the morphology and physiology of neurons.
Avila, Jesús, Hernández Pérez, Félix, Lucas, José J., Pérez Martínez, María Mar   +3 more
core   +1 more source

Physiological and biochemical changes in human spaceflights [PDF]

فصلنامه ابن سینا, 2017
At the moment, a variety of disasters including climate changes and meteorite fall threaten human society on the earth. So, scientists believe that it is important to explore viable alternative planets in the Solar System to ensure survival of the human ...
M Panjehpour, A Ghasemi
doaj  

Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.

PLoS Genetics, 2019
Evolutionary adaptation to extreme environments often requires coordinated changes in multiple intersecting physiological pathways, but how such multi-trait adaptation occurs remains unresolved.
Rena M Schweizer, Jonathan P Velotta, Catherine M Ivy, Matthew R Jones, Sarah M Muir, Gideon S Bradburd, Jay F Storz, Graham R Scott, Zachary A Cheviron   +8 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Climate change adaptation in industry and business [PDF]

, 2013
This report delivers a best practice framework to integrate financial risk assessment, governance and disclosure with existing governance principles around climate change adaptation.AbstractThe Australian business community has long been aware of the ...
Jason West, David Brereton
core  

Avoid, attack or do both? Behavioral and physiological adaptations in natural enemies faced with novel hosts

BMC Evolutionary Biology, 2005
Background Confronted with well-defended, novel hosts, should an enemy invest in avoidance of these hosts (behavioral adaptation), neutralization of the defensive innovation (physiological adaptation) or both?
Brown Sam P, Vacher Corinne, Hochberg Michael E   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Explaining bathymetric diversity patterns in marine benthic invertebrates and demersal fishes: physiological contributions to adaptation of life at depth

, 2014
Bathymetric biodiversity patterns of marine benthic invertebrates and demersal fishes have been identified in the extant fauna of the deep continental margins.
Brown, Alastair, Thatje, Sven
core   +1 more source

Phenotypic flexibility and the evolution of organismal design [PDF]

, 2003
Evolutionary biologists often use phenotypic differences between species and between individuals to gain an understanding of organismal design. The focus of much recent attention has been on developmental plasticity – the environmentally induced ...
Piersma, T, Drent, Jan,, Piersma, Theunis,, Piersma, T; id_orcid, Drent, J   +4 more
core   +2 more sources

Physiological and Genetic Basis of High-Altitude Indigenous Animals’ Adaptation to Hypoxic Environments

Animals
Adaptation is one of the fundamental characteristics of life activities; humans and animals inhabiting high altitudes are well adapted to hypobaric hypoxic environments, and studies on the mechanisms of this adaptation emerged a hundred years ago.
Pengfei Zhao, Shaobin Li, Zhaohua He, Xiong Ma   +3 more
doaj   +1 more source