Results 81 to 90 of about 1,276,486 (299)

Locating QTL Controlling the Yield-Related Traits in Perennial Chinese Rice “Shendao3^#”

Agriculture
Shendao3# (SD3#) exhibits perennial characteristics. Identifying the QTLs underlying the yield-related traits in SD3# provides a theoretical basis for future perennial rice breeding.
Yuxin Yan, Jiuyan Lu, Meilin Wu, Tingshen Peng, Lin Tan, Wenbin Nan, Xiaojian Qin, Ming Li, Junyi Gong, Yongshu Liang   +9 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Milk Metabolomics Data Reveal the Energy Balance of Individual Dairy Cows in Early Lactation

Scientific Reports, 2018
In early lactation, dairy cows typically have a negative energy balance which has been related to metabolic disorders, compromised health and fertility, and reduced productive lifespan.
Wei Xu, Jacques Vervoort, Edoardo Saccenti, Renny van Hoeij, Bas Kemp, Ariette van Knegsel   +5 more
doaj   +1 more source

Neural Mechanisms of Strategic Adaptation in Attentional Flexibility [PDF]

, 2020
Anthony W. Sali, Jiefeng Jiang, Tobias Egner   +2 more
openalex   +1 more source

Adaptation, ‘Adaptation’, and Adaptation: Zizek and the Commonplace

Film-Philosophy, 2004
_Adaptation_ is the film this article is about. The rules of electronic articles require that it be quoted with underscores. \'Adaptation\' is the subject and title of this articleand so should be indicated with inverted commas. Adaptation, without underlining and without quotation marks, is just adaptation, the thing itself.
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cross-cultural adaptation and validation of the Canadian Haemophilia Outcomes-Kids’ Life Assessment Tool (CHO-KLAT) in Côte d’Ivoire (the Ivory Coast) [PDF]

, 2020
Catherine Lambert, N’Dogomo Meité, Ibrahima Sanogo, Sébastien Lobet, Cédric Hermans, Séverine Henrard, Victor S. Blanchette, Nancy L. Young   +7 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source