Results 101 to 110 of about 5,183,374 (302)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Mind, mechanism, and adaptive behavior
, 1937 MIND, MECHANISM, AND ADAPTIVE BEHAVIOR Mind, mechanism, and adaptive behavior (44) (-
Hull, Clark Leonard
core +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Caregivers’ Perspective About the Levels of Sensory Processing Problems in Children With Autism
Journal of Client-centered Nursing Care, 2018 Background: Children with autism should interact and get along with their surrounding environment. Therefore, the researchers must try to explain the reasons of challenges in their adaptive behaviors.
Mohannad Mohammad Husni Amireh +1 more
doaj
What about me? Factors affecting individual adaptive coping capacity across different populations [PDF]
, 2013 When and why will people adapt to climate change? We conducted a number of studies examining the psychological drivers of individual adaptation to climate change across different populations. We used a variety of methodologies including interviews,
Stephen Lewandowsky +2 more
core
, 2015 How to achieve dominance in a group is a recurrent challenge for individuals of many species, including humans. Previous research indicates that both relationship status and contraceptive use appear to moderate women’s testosterone levels.
Cobey, Kelly +3 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
COMPLEX ADAPTIVE BEHAVIOR OF INVESTORS TO MARKET DYNAMICS: A PLS-SEM ANALYSIS [PDF]
Journal of Applied Structural Equation Modeling, 2023 Ahmed El Oubani
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source