Results 71 to 80 of about 5,183,374 (302)

To what extent does g impact on conceptual, practical and social adaptive functioning in clinically referred children? [PDF]

open access: yes, 2013
BACKGROUND: Previous analyses have found variable results when evaluating the size of the association between intellectual ability and adaptive functioning in individuals with impaired function.
Murray, Aja Louise   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Tablet Apps to Support First School Inclusion of Children With Autism Spectrum Disorders (ASD) in Mainstream Classrooms: A Pilot Study

open access: yesFrontiers in Psychology, 2018
The inclusion of children with autism spectrum disorders (ASD) in mainstream classrooms is dramatically impeded by their difficulties in socio-adaptive behaviors.
Charles Fage   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Caution as a Response to Scientific Uncertainty: A Groundwater Game Experiment

open access: yesInternational Journal of the Commons
Understanding and managing uncertainty is critical for robust governance. In groundwater management, where collaborative, community-based governance is increasingly common, scientific uncertainty about hydrological conditions could pose challenges to ...
Minwoo Ahn   +2 more
doaj   +1 more source

A Case for Eustress in Grazing Animals

open access: yesFrontiers in Veterinary Science, 2019
Herbivores grazing in extensive systems are exposed to a series of challenges, rooted in the inherent spatial and temporal variability of their environment that potentially constrain their health, nutrition, and welfare.
Juan J. Villalba, Xavier Manteca
doaj   +1 more source

Asymptotic behavior of the rate of adaptation

open access: yesThe Annals of Applied Probability, 2010
We consider the accumulation of beneficial and deleterious mutations in large asexual populations. The rate of adaptation is affected by the total mutation rate, proportion of beneficial mutations and population size $N$. We show that regardless of mutation rates, as long as the proportion of beneficial mutations is strictly positive, the adaptation ...
Yu, F, Etheridge, A, Cuthbertson, C
openaire   +6 more sources

Affective-Associative Two-Process theory : A neural network investigation of adaptive behaviour in differential outcomes training

open access: yes, 2017
In this article we present a novel neural network implementation of Associative Two-Process (ATP) theory based on an Actor–Critic-like architecture.
Billing, Erik,   +2 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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