Results 71 to 80 of about 944,913 (317)

Curriculum Design and Sim2Real Transfer for Reinforcement Learning in Robotic Dual-Arm Assembly

Machines
Robotic systems are crucial in modern manufacturing. Complex assembly tasks require the collaboration of multiple robots. Their orchestration is challenging due to tight tolerances and precision requirements.
Konstantin Wrede, Sebastian Zarnack, Robert Lange, Oliver Donath, Tommy Wohlfahrt, Ute Feldmann   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Multi-drug infusion control using model reference adaptive algorithm [PDF]

, 2011
Control of physiological states such as mean arterial pressure (MAP) has been successfully achieved using single drug by different control algorithms. Multi-drug delivery demonstrates a significantly challenging task as compared to control with a single ...
Mahieddine, Fatima, Hossain, Alamgir, Enbiya, Saleh   +2 more
core  

Nonconserved epitopes dominate reverse preexisting T cell immunity in COVID-19 convalescents

Signal Transduction and Targeted Therapy
The herd immunity against SARS-CoV-2 is continuously consolidated across the world during the ongoing pandemic. However, the potential function of the nonconserved epitopes in the reverse preexisting cross-reactivity induced by SARS-CoV-2 to other human ...
Xin Wang, Jie Zhang, Maoshun Liu, Yuanyuan Guo, Peipei Guo, Xiaonan Yang, Bingli Shang, Min Li, Jinmin Tian, Ting Zhang, Xi Wang, Ronghua Jin, Jikun Zhou, George F. Gao, Jun Liu   +14 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Adaptive Neuro-Genetic Control of Chaos applied to the Attitude Control Problem [PDF]

, 1997
Conventional adaptive control techniques have for the most part been based on methods for linear or weakly non-linear systems. More recently neural network and genetic algorithm controllers have started to be applied to complex, non-linear dynamic ...
Dimitris C. Dracopoulos, Antonia J. Jones, Jones, A.J., Dracopoulos, D.   +3 more
core   +1 more source

A Tutorial on Robust Control, Adaptive Control and Robust Adaptive Control—Application to Robotic Manipulators

Inventions, 2019
A tutorial on robust control, adaptive control, robust adaptive control and adaptive control of robotic manipulators is presented in a systematic manner. Some limitations of the above methods are also illustrated.
Bin Wei
doaj   +1 more source

Concurrency control for adaptive indexing [PDF]

Proceedings of the VLDB Endowment, 2012
Adaptive indexing initializes and optimizes indexes incrementally, as a side effect of query processing. The goal is to achieve the benefits of indexes while hiding or minimizing the costs of index creation. However, index-optimizing side effects seem to turn read-only queries into update transactions that might, for example, create lock contention.
G. Graefe, F Halim, S. Idreos (Stratos), H. Kuno, S. Manegold (Stefan)   +4 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source