Results 81 to 90 of about 944,913 (317)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
L1-Adaptive Control for Anesthesia Delivery [PDF]
, 2010 In this paper, we discuss the first application of recently developed L1-adaptive control methods for the closed-loop control of anesthesia delivery during surgery.
Ralph, Matthew A.
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
An asymptotic scaling analysis of LQ performance of an approximate adaptive control design [PDF]
, 2002 We consider the adaptive tracking problem for a chain of integrators, where the uncertainty is static and functional. The uncertainty is specified by L2/L∞ or weighted L2/L∞ norm bounds. We analyse a standard Lyapunov-based adaptive design which utilises
Szepesvari, Cs., Rogers, E., French, M.
core
Adaptive, cautious, predictive control with Gaussian process priors [PDF]
, 2003 Nonparametric Gaussian Process models, a Bayesian statistics approach, are used to implement a nonlinear adaptive control law. Predictions, including propagation of the state uncertainty are made over a k-step horizon.
Sbarbaro, D. +13 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Towards a performance theory of robust adaptive control [PDF]
, 2004 We consider standard robust adaptive control designs based on the dead-zone and projection modifications, and compare their performance w.r.t. a worst case transient cost functional penalising the L∞ norm of the output, control and control derivative. If
Sanei, A., French, M.
core
A biased approach to nonlinear robust stability and performance with applications to adaptive control [PDF]
, 2012 The nonlinear robust stability theory of Georgiou and Smith [IEEE Trans. Automat. Control, 42 (1997), pp. 1200–1229] is generalized to the case of notions of stability with bias terms.
Bian, Wenming, French, Mark
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source