Results 221 to 230 of about 41,981 (294)

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

Beyond Negated Identity: Mediating the World History Classroom through Adorno's Negative Dialectics

open access: yesEducational Theory, Volume 76, Issue 3, Page 395-419, June 2026.
Abstract This article centers on Adorno's negative dialectics to account for experiences of alienation and marginalization within the world history classroom. It begins with the problem of how marginalization occurs in high school world history classrooms with predominantly Black and Latinx students.
Tadashi Dozono
wiley   +1 more source

Microbial Controls on Dissolved Organic Nitrogen Cycling During Long‐Term Degradation Experiments

open access: yesGeophysical Research Letters, Volume 53, Issue 10, 28 May 2026.
Abstract Dissolved organic nitrogen (DON) is critical for marine microbial growth by providing carbon and nitrogen. Although DON is rapidly cycled, some compounds within this pool can persist for long‐periods of time. To better understand how DON is cycled by marine microorganisms, we conducted 548‐day incubations using surface‐derived dissolved ...
Richard LaBrie   +5 more
wiley   +1 more source

Ocean Circulation Modulating the Nutrient Distribution and Fluxes at Regional and Fine Scales: A Case Study in the Northwestern Mediterranean Sea

open access: yesGeophysical Research Letters, Volume 53, Issue 10, 28 May 2026.
Abstract In the oligotrophic ocean, nutrient distribution plays a key role in controlling primary production via upward fluxes. In spring 2023, the BioSWOT‐Med cruise investigated how fine‐scale ocean dynamics influence nutrient availability in the Mediterranean Sea.
A. Joël   +16 more
wiley   +1 more source

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