Results 41 to 50 of about 565,752 (296)
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Ecological and Human Community Resilience in Response to Natural Disasters
Ecological resilience, adaptive cycles, and panarchy are all concepts that have been developed to explain abrupt and often surprising changes in complex socio-ecological systems that are prone to disturbances.
Lance Gunderson
doaj +1 more source
In order to improve the fuel economy of an extended-range electric vehicle with the engine-generator, an adaptive energy management strategy has been proposed in this paper.
Xiaodong Wu, Yanhao Gu, Min Xu
doaj +1 more source
Atmospheric water harvesting by MOF-based devices is critically dependent on weather conditions. Here, the authors report a MOF-based adaptive water harvesting system capable of adapting its cycles to temperature and relative humidity fluctuations ...
Husam A. Almassad +4 more
doaj +1 more source
Adaptive evolution of larvae and life cycles
The larval patterns of marine invertebrates pose intriguing questions for both evolutionary and developmental biologists. However, combined investigations have been rare. Quantitative models analyze the selective factors that drive evolutionary change in larval nutrition and timing of metamorphosis.
Department of Zoology, University of Florida, PO Box 118525, University of Florida, Gainesville, FL 32611-8525, USA. ( host institution ) +1 more
openaire +3 more sources
Lunar cycles of reproduction in the clown anemonefish Amphiprion percula: individual-level strategies and population-level patterns [PDF]
Lunar cycles of reproduction are a widespread phenomenon in marine invertebrates and vertebrates. It is common practice to infer the adaptive value of this behavior based on the population level pattern.
Seymour, Jeremiah R.
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Inspired individuals and charismatic leaders
Recent fieldwork at Pre-Pottery Neolithic (PPN) Göbeklitepe has revealed a life-size limestone statue of a wild boar in Special Building D, which, alongside discoveries from nearby contemporaneous sites, broadens our understanding of late hunter-forager
Lee Clare
doaj +1 more source
Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer: A Promising Approach. [PDF]
Locally advanced pancreatic cancer (LAPC) is characterized by poor prognosis and low response durability with standard-of-care chemotherapy or chemoradiotherapy treatment.
Cao, Minsong +6 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

