Results 81 to 90 of about 33,794 (307)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NOVEL NUMERICAL PROCEDURES FOR LIMIT ANALYSIS OF STRUCTURES: MESH-FREE METHODS AND MATHEMATICAL PROGRAMMING [PDF]
, 2010 Current research in the field of limit analysis is focussing on the development of numerical tools which are sufficiently efficient and robust to be used in engineering practice.
Le, Canh
core
Optimal tracking control of the coal mining face fluid supply system via adaptive dynamic programming. [PDF]
Sci Rep, 2023 Zeng X, Wang D.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Systems Science & Control EngineeringLearning controllers for nonlinear complex systems using data-driven model-free adaptive dynamic programming (ADP) algorithms is a challenging problem.
Timotei Lala
doaj +1 more source
Neural Adaptive H∞ Sliding-Mode Control for Uncertain Nonlinear Systems with Disturbances Using Adaptive Dynamic Programming. [PDF]
Entropy (Basel), 2023 Huang Y, Zhang Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Driving-Cycle-Adaptive Energy Management Strategy for Hybrid Energy Storage Electric Vehicles
World Electric Vehicle JournalThe energy management strategy (EMS) is a critical technology for pure electric vehicles equipped with hybrid energy storage systems. This study addresses the challenges of limited adaptability to driving cycles and significant battery capacity ...
Zhaocheng Lu +3 more
doaj +1 more source
Model-Free Composite Control of Flexible Manipulators Based on Adaptive Dynamic Programming
Complexity, 2018 This paper studies the problems of tip position regulation and vibration suppression of flexible manipulators without using the model. Because of the two-timescale characteristics of flexible manipulators, applying the existing model-free control methods
Chunyu Yang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source