Results 61 to 70 of about 33,794 (307)

Nonlinear Control of Ship-Mounted Rotary Crane Based on Adaptive Dynamic Programming

IEEE Access
As a crucial component in marine transportation, the precision of ship-mounted rotary cranes directly impacts the efficiency and safety of lifting operations.
Huan Xi, Qiangying Wu, Huimin Ouyang
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Data‐based robust optimal control of discrete‐time systems with uncertainties via adaptive dynamic programming

, 2023
In this article, a new data-based adaptive dynamic programming algorithm is proposed to solve the optimal control policy for discrete-time systems with uncertainties. Firstly, for uncertain systems, the corresponding Hamiltonian function is designed, and
Jian Xu, Xing, Zuoxia, Xu, Jian, Chen, Zhe; id_orcid, Zhe Chen, Liu, Yang, Yang Liu, Zuoxia Xing   +7 more
core   +1 more source

Energy management strategy for hybrid electric vehicles based on adaptive equivalent consumption minimization strategy and mode switching with variable thresholds

Science Progress, 2020
To improve the real-time capability, adaptivity, and efficiency of the energy management strategy in the actual driving cycle, a real-time energy management strategy is investigated for commute hybrid electric vehicles, which integrates mode switching ...
Yang Li, Xiaohong Jiao
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Event-Triggered Output Feedback Control for a Class of Nonlinear Systems via Disturbance Observer and Adaptive Dynamic Programming

, 2023
An event-triggered output feedback control approach is proposed via a disturbance observer and adaptive dynamic programming (ADP). The solution starts by constructing a nonlinear disturbance observer, which only depends on the measurement of system ...
Yue, W, Wu, J, Aaron Liu, Yang, Y, Jinran Wu, Fan, X, Shuocong Geng, Weinan Gao, Wenbin Yue, Liu, A, Geng, S, Yang Yang, Gao, W, Xin Fan   +13 more
core   +1 more source

Dynamically adapting the degree of parallelism with reflexive programs

, 1996
In this paper we present a new method for achieving a higher cost-efficiency on parallel computers. We insert routines into a program which detect the amount of computational work without using problem-specific parameters and adapt the number of used CPUs at runtime under given speedup/efficiency constraints.
Reimer, Niels, Haenssgen, Stefan, Tichy, Walter F.   +2 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source