Results 111 to 120 of about 277,643 (313)

Lethal Aggression in Pan Is Better Explained by Adaptive Strategies Than Human Impacts [PDF]

, 2014
Observations of chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) provide valuable comparative data for understanding the significance of conspecific killing. Two kinds of hypothesis have been proposed. Lethal violence is sometimes concluded to be
Mundry, R., David Morgan, Fruth, B. ; https://orcid.org/, Anne E. Pusey, Simmons, N., Wittig, Roman Martin, Gilby, I., Tetsuro Matsuzawa, Crickette Sanz, Roger Mundry, Zuberbuehler, Klaus, Muller, Martin N, Zuberbühler, Klaus, Christophe Boesch, Wrangham, Richard, Sanz, Crickette, Noriko Itoh, White, Francis, Pruetz, J., Waller, M., Lloyd, Julia, Michio Nakamura, Richard W. Wrangham, Gilby, Ian C, Kathelijne Koops, Wittig, Roman M., Deus C. Mjungu, Muller, M., Barbara Fruth, Simmons, Nicole, Hohmann, G., Morgan, David, Wilson, Micahel, Koops, Kathelijne, Hobaiter, Catherine, White, F., Wrangham, Richard W, Watts, D., Waller, Michael, Schel, Anne Marijke, Wrangham, R., Pruetz, Jill, Pusey, A., Nicole Simmons, Wittig, R., Koops, K., Wilson, M., Catherine L. Hobaiter, Fruth, Barbara, Lloyd, Julia N, Hashimoto, C., John C. Mitani, Zuberbühler, K., Ian C. Gilby, Lloyd, Julia N., Riedel, Julia, Michael L. Wilson, Lloyd, J., Wittig, Roman, Matsuzawa, T., Schel, A., Mundry, R. ; https://orcid.org/, Watts, David P, Morgan, D., Schel, Anne M, Furuichi, T., Watts, David P., Hohmann, Gottifred, Mitani, John C., Takeshi Furuichi, Gottfried Hohmann, David P. Watts, Boesch, C., Mundry, Roger, Martin N. Muller, Pusey, Anne E, Waller, Michel, Fruth, B., Boesch, C. ; https://orcid.org/, Pusey, Anne E., Hashimoto, Chie, Muller, Martin N., Nakamura, Michio, Matsuzawa, Tetsuro, Julia N. Lloyd, Jill Pruetz, Itoh, N., Wittig, Roman M, White, Frances, Mjungu, Deus C., Pusey, Anne, Wilson, Michael L, Nakamura, M., Itoh, Noriko, Mitani, J., Anne M. Schel, Sanz, C., Riedel, J., Roman M. Wittig, Julia Riedel, Gilby, Ian C., Hohmann, Gottfried, Hobaiter, Catherine L, Mjungu, Deus C, Wilson, Michael L., Wrangham, Richard W., Mitani, John, Schel, Anne, Muller, Martin, Boesch, Christophe, Wrangham, Rcihard, Chie Hashimoto, Gilby, Ian, Watts, David, Hohmann, G. ; https://orcid.org/, Wittig, R. ; https://orcid.org/, Klaus Zuberbühler, Schel, Anne M., Mitani, John C, Mjungu, D., Hobaiter, Cat, Hobaiter, C., Mjungu, Dues, Frances White, Furuichi, Takeshi, Michel Waller   +125 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Self-Adaptive Multiple Evolution algorithms for Image Segmentation using Multilevel Thresholding

, 2015
Multilevel thresholding based on Otsu method is one of the most popular image segmentation techniques. However, when the number of thresholds increases, the consumption of CPU time grows exponentially.
Liling Sun, Sun LL(孙丽玲), Na Lin, Hu JT(胡静涛), Chen HN(陈瀚宁), Hanning Chen, Jingtao Hu, Zhang QC(张巧翠), Qiaocui Zhang   +8 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Insects with similar social complexity show convergent patterns of adaptive molecular evolution

, 2018
Eusociality has independently evolved multiple times in the hymenoptera, but the patterns of adaptive molecular evolution underlying the evolution and elaboration of eusociality remain uncertain.
Rodrigues, André, Toth, Amy, Dogantzis, Kathleen, Beani, Laura, Harpur, Brock, Zayed, Amro   +5 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nonconserved epitopes dominate reverse preexisting T cell immunity in COVID-19 convalescents

Signal Transduction and Targeted Therapy
The herd immunity against SARS-CoV-2 is continuously consolidated across the world during the ongoing pandemic. However, the potential function of the nonconserved epitopes in the reverse preexisting cross-reactivity induced by SARS-CoV-2 to other human ...
Xin Wang, Jie Zhang, Maoshun Liu, Yuanyuan Guo, Peipei Guo, Xiaonan Yang, Bingli Shang, Min Li, Jinmin Tian, Ting Zhang, Xi Wang, Ronghua Jin, Jikun Zhou, George F. Gao, Jun Liu   +14 more
doaj   +1 more source

Evolution of Xilinx adaptive computing

, 2022
reservedIl lavoro di tesi è svolto sull'argomento dell' adaptive computing e come sia evoluto nel tempo, parlando in specifico degli dispositivi della ...
SOLONARU, BOGDAN
core