Results 231 to 240 of about 1,014,656 (349)

Evolutionary Diversification and Adaptive Evolution Analysis of the Plant HD-Zip IV Subfamily. [PDF]

Genes (Basel)
Li Y, Liu Z, Qanmber G, Liu L, Shi H, Guo Y, Yu M, Hussain G, Peng F, Zheng K, Li F.   +10 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Metabolic plasticity and adaptive evolution in <i>Fragaria vesca</i>: bridging wild diversity to crop improvement. [PDF]

Front Plant Sci
Pérez-Martín JE, Bonte D, Osorio S, Posé D.   +3 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Regulation of the amh gene promoter activity by SF-1 in sex-reversing Cheilinus undulatus and its adaptive evolution. [PDF]

BMC Genomics
Bu S, Zhu Y, Ji X, Zhang W, Hu C, Wen X, Luo J.   +6 more
europepmc   +1 more source

MOESM2 of Generation of a platform strain for ionic liquid tolerance using adaptive laboratory evolution

, 2017
Elsayed Mohamed, Shizeng Wang, Rebecca M. Lennen, Markus HerrgĂĽrd, Blake Simmons, Steven W. Singer, Adam M. Feist   +6 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Comparative Mitogenomics of <i>Channa pyrophthalmus</i> Unveils Orogeny-Driven Speciation and Lineage-Specific Adaptive Evolution in Snakeheads. [PDF]

Animals (Basel)
Luo Q, Liu J, Liu J, Ou M, Fei S, Liu H, Zhang X, Zhao J.   +7 more
europepmc   +1 more source

Minimizing transportation cost of a joint inventory location model using modified adaptive differential evolution algorithm

, 2011
Abhishek Jha, Keshav Somani, Manoj Kumar Tiwari, Felix T.S. Chan, Kiran Fernandes   +4 more
openalex   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source