Results 71 to 80 of about 165,941 (265)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A Unified View of Adaptive Variable-Metric Projection Algorithms
EURASIP Journal on Advances in Signal Processing, 2009 We present a unified analytic tool named variable-metric adaptive projected subgradient method (V-APSM) that encompasses the important family of adaptive variable-metric projection algorithms. The family includes the transform-domain adaptive filter, the
Masahiro Yukawa, Isao Yamada
doaj +1 more source
AREA AND POWER EFFICIENT LEAST MEAN SQUARE ADAPTIVE FILTER USING APPROXIMATE ARITHMETIC [PDF]
Proceedings on Engineering SciencesThe efficiency of a digital signal processing system heavily relies on the performance of multipliers, which are crucial arithmetic functional units. Approximate arithmetic techniques have emerged as a promising approach to significantly reduce circuit ...
G. R. L. V. N. S. Raju +5 more
doaj +1 more source
Optimization of adaptive filter control parameters for non-invasive fetal electrocardiogram extraction. [PDF]
PLoS One, 2022 Kahankova R, Mikolasova M, Martinek R.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
A Low-Cost Multistage Cascaded Adaptive Filter Configuration for Noise Reduction in Phonocardiogram Signal. [PDF]
J Healthc Eng, 2022 Pauline SH +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
A New Robust Adaptive Filter Aided by Machine Learning Method for SINS/DVL Integrated Navigation System. [PDF]
Sensors (Basel), 2022 Zhu J, Li A, Qin F, Chang L.
europepmc +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source