Results 81 to 90 of about 5,059,929 (339)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Spectral filtering for the resolution of the Gibbs phenomenon in MPI applications [PDF]

, 2016
open3Polynomial interpolation on the node points of Lissajous curves using Chebyshev series is an e effective way for a fast image reconstruction in Magnetic Particle Imaging.
De Marchi, Stefano, Erb, Wolfgang, Marchetti, Francesco   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A Novel Optimal Robust Adaptive Scheme for Accurate GNSS RTK/INS Tightly Coupled Integration in Urban Environments

Remote Sensing, 2023
Modern navigation systems are inseparable from an integrated solution consisting of a global navigation satellite system (GNSS) and an inertial navigation system (INS) since they serve as an important cornerstone of national comprehensive positioning ...
Jiaji Wu, Jinguang Jiang, Chao Zhang, Yuying Li, Peihui Yan, Xiaoliang Meng   +5 more
doaj   +1 more source

Reflectance Adaptive Filtering Improves Intrinsic Image Estimation

, 2017
Separating an image into reflectance and shading layers poses a challenge for learning approaches because no large corpus of precise and realistic ground truth decompositions exists. The Intrinsic Images in the Wild~(IIW) dataset provides a sparse set of
Gehler, Peter V., Nestmeyer, Thomas
core   +1 more source

Adaptive pre-filtering techniques for colour image analysis [PDF]

, 2007
One important step in the process of colour image segmentation is to reduce the errors caused by image noise and local colour inhomogeneities. This can be achieved by filtering the data with a smoothing operator that eliminates the noise and the ...
Ilea, Dana E., Whelan, Paul F.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Modified LMS Strategies Using Internal Model Control for Active Noise and Vibration Control Systems

Applied Sciences, 2018
Traditional adaptive filtering algorithms are non-recursive systems that cannot use a time-variant reference input in real time and are not appropriate for control signals with uncertainties and unanticipated conditions. The main purpose of this research
Byeongil Kim, Jong-Yun Yoon
doaj   +1 more source

Underwater Geomagnetic Localization Based on Adaptive Fission Particle-Matching Technology

Journal of Marine Science and Engineering, 2023
The geomagnetic field constitutes a massive fingerprint database, and its unique structure provides potential position correction information. In recent years, particle filter technology has received more attention in the context of robot navigation ...
Huapeng Yu, Ziyuan Li, Wentie Yang, Tongsheng Shen, Dalei Liang, Qinyuan He   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source