Results 71 to 80 of about 5,059,929 (339)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Adaptive filter with Riemannian manifold constraint

open access: yesScientific Reports, 2023
The adaptive filtering theory has been extensively developed, and most of the proposed algorithms work under the assumption of Euclidean space. However, in many applications, the data to be processed comes from a non-linear manifold.
Jose Mejia   +3 more
doaj   +1 more source

Proportionate Adaptive Filtering for Block-Sparse System Identification [PDF]

open access: yesIEEE/ACM Transactions on Audio Speech and Language Processing, 2015
In this paper, a new family of proportionate normalized least mean square (PNLMS) adaptive algorithms that improve the performance of identifying block-sparse systems is proposed.
Jianming Liu, S. Grant
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Kalman Filtering Blind Adaptive Multi-user Detector Based on Tracking Algorithm of Signal Subspace

open access: yesInformation, 2015
Multi-user detection is an effective method to reduce multiple access interference in code division multiple access (CDMA) systems. This paper discusses a signal subspace based blind adaptive multiuser detector and a Kalman filtering blind adaptive ...
Liqing Zhou   +5 more
doaj   +1 more source

Feature Extracting in the Presence of Environmental Noise, using Subband Adaptive Filtering [PDF]

open access: yes, 2009
In this work, a new feature extracting method in noisy environments is proposed. The approach is based on subband decomposition of speech signals followed by adaptive filtering in the noisiest subbbands of speech.
Samad, Salina Abdul
core  

A Tuner that Accelerates Parameters

open access: yes, 1998
We propose a tuner, suitable for adaptive control and (in its discrete-time version) adaptive filtering applications, that sets the second derivative of the parameter estimates rather than the first derivative as is done in the overwhelming majority of ...
Atkinson, Paulo A, Pait, Felipe M.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

An Improved Adaptive Weighted Mean Filtering Approach for Metallographic Image Processing

open access: yesJournal of Intelligent Systems, 2021
As noise brings great error in the analysis of metallographic images, an adaptive weighted mean filtering method proposed to overcome the shortcomings of the standard mean filtering method.
Shao Chonglei, Kaur Preet, Kumar Rajeev
doaj   +1 more source

Adaptive Spatiotemporal SVD Clutter Filtering for Ultrafast Doppler Imaging Using Similarity of Spatial Singular Vectors

open access: yesIEEE Transactions on Medical Imaging, 2018
Singular value decomposition of ultrafast imaging ultrasonic data sets has recently been shown to build a vector basis far more adapted to the discrimination of tissue and blood flow than the classical Fourier basis, improving by large factor clutter ...
J. Baranger   +5 more
semanticscholar   +1 more source

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