Results 71 to 80 of about 71,436 (268)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Image Restoration with Two-Dimensional Adaptive Filter Algorithms

Iranian Journal of Electrical and Electronic Engineering, 2011
Two-dimensional (TD) adaptive filtering is a technique that can be applied to many image, and signal processing applications. This paper extends the one-dimensional adaptive filter algorithms to TD structures and the novel TD adaptive filters are ...
M. Shams Esfand Abadi, S. Nikbakht
doaj  

Convex Combined Adaptive Filtering Algorithm for Acoustic Echo Cancellation in Hostile Environments

IEEE Access, 2018
Research into combined adaptive filters has been attracting considerable attention; the performance of which is generally superior to that of the individual component filters.
Ying-Ren Chien, Jin Li-You
doaj   +1 more source

The effect of pre-aggregation scale on spatially adaptive filters. [PDF]

Spat Spatiotemporal Epidemiol, 2022
Haynes D, Hughes KD, Rau A, Joseph AM.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Joint application of hybrid iterative reconstruction and adaptive filters on neck-and-shoulder CT imaging: A clinical evaluation. [PDF]

J Appl Clin Med Phys, 2022
Jin W, Ma Y, Han D, Xie X, Zhang W, Wu Y, Zhang G.   +6 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Kalman Filter for Multilinear Forms and Its Connection with Tensorial Adaptive Filters. [PDF]

Sensors (Basel), 2021
Dogariu LM, Paleologu C, Benesty J, Stanciu CL, Oprea CC, Ciochină S.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Applications of the Kalman Filter in Physical Processes: A Review

Applied Sciences
This article outlines various specialized adaptations of the Kalman Filter designed to address specific estimation challenges across different domains of Physics.
Ioanna Anagnostaki, Vassilis Anastassopoulos, Georgia Koukiou   +2 more
doaj   +1 more source