Results 81 to 90 of about 66,787 (268)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Highlight of lung nodule candidates in chest radiographs by convergence filters

open access: yesIngeniería, 2014
This paper describes the development of a method that highlights suspicious areas of lung nodules on chest radiographs. Lung nodules are lesions found in the lung region, which are the first indicators of the presence of cancerous tumors.
Sergio Alejandro Duarte Pacheco   +2 more
doaj   +1 more source

A Kalman Filter for Multilinear Forms and Its Connection with Tensorial Adaptive Filters. [PDF]

open access: yesSensors (Basel), 2021
Dogariu LM   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Applications of the Kalman Filter in Physical Processes: A Review

open access: yesApplied Sciences
This article outlines various specialized adaptations of the Kalman Filter designed to address specific estimation challenges across different domains of Physics.
Ioanna Anagnostaki   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Blind adaptive receiver for uplink multiuser massive MIMO systems

open access: yesETRI Journal, 2019
Herein, we consider uplink multiuser massive multiple‐input multiple‐output systems when multiple users transmit information symbols to a base station (BS) by applying simple space‐time block coding (STBC).
Joonwoo Shin, Bangwon Seo
doaj   +1 more source

Recursive algorithms of adaptive lattice filters adjustment

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2016
The authors analyse the algorithms intended for correction of adaptive lattice filters (ALF) parameters under K-rank (K ≥ 1) modification of estimate correlation matrix within a "sliding" over the time (range) data window.
D. I. Lekhovytskiy   +3 more
doaj   +1 more source

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