Results 61 to 70 of about 71,436 (268)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
IEEE AccessElectrodermal activity (EDA) shows a significant correlation with activation of the autonomic nervous system (ANS) activation. Regular ambulatory monitoring via wearables and consequent inference of ANS activation has a wide range of applications ...
Md. Rafiul Amin +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
An Improved Variable Structure Adaptive Filter Design and Analysis for Acoustic Echo Cancellation [PDF]
Radioengineering, 2015 In this research an advance variable structure adaptive Multiple Sub-Filters (MSF) based algorithm for single channel Acoustic Echo Cancellation (AEC) is proposed and analyzed.
A. Kar, M. Chandra
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The Joint Adaptive Kalman Filter (JAKF) for Vehicle Motion State Estimation
Sensors, 2016 This paper proposes a multi-sensory Joint Adaptive Kalman Filter (JAKF) through extending innovation-based adaptive estimation (IAE) to estimate the motion state of the moving vehicles ahead.
Siwei Gao +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
SD LMS L-Filters for Filtration of Gray Level Images in Timespatial Domain Based on GLCM Features
Advances in Electrical and Electronic Engineering, 2008 In this paper, the new kind of adaptive signal-dependent LMS L-filter for suppression of a mixed noise in greyscale images is developed. It is based on the texture parameter measurement as modification of spatial impulse detector structure. Moreover, the
Robert Hudec +2 more
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Phase-amplitude coupling-based adaptive filters for neural signal decoding. [PDF]
Front Neurosci, 2023 Li J, Qi Y, Pan G.
europepmc +1 more source