Results 41 to 50 of about 43,903 (287)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Measuring and Managing Answer Quality for Online Data-Intensive Services

, 2015
Online data-intensive services parallelize query execution across distributed software components. Interactive response time is a priority, so online query executions return answers without waiting for slow running components to finish.
Elnikety, Sameh, He, Yuxiong, Kelley, Jaimie, Morris, Nathaniel, Stewart, Christopher, Tiwari, Devesh   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

KOORDINASI PEMBANGKIT LISTRIK TENAGA SURYA (PLTS) BERBASIS ALGORITMA MULTIPLE SEQUENCE ALIGNMENT (MSA)

Multitek Indonesia, 2023
Solar Power Plants (PLTS) can be composed of many solar panels and connected with many loads at the output. The reliability of an electric power system is the guarantee of an electric power supply that can always meet ...
Denny Irawan, Eka Putra Prastya, Alief Hidayah   +2 more
doaj   +1 more source

PMU-Based ROCOF Measurements: Uncertainty Limits and Metrological Significance in Power System Applications

, 2019
In modern power systems, the Rate-of-Change-of-Frequency (ROCOF) may be largely employed in Wide Area Monitoring, Protection and Control (WAMPAC) applications. However, a standard approach towards ROCOF measurements is still missing.
Derviskadic, Asja, Frigo, Guglielmo, Paolone, Mario, Zuo, Yihui   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Real-Time Adaptive Corrective Control of Short-Term Voltage Stability

IEEE Access
Although several data-driven approaches for short-term voltage stability (STVS) assessment have been proposed, most of them do not extend to corrective control actions nor consider the joint dynamics of generation and load. To address this gap, this work
Estefania A. Tapia Suarez, D. Graciela Colome, Jose L. Rueda Torres   +2 more
doaj   +1 more source

An adaptive vector control method for inverter‐based stand‐alone microgrids considering voltage reduction and load shedding schemes

IET Generation, Transmission & Distribution, 2023
The droop mechanism is widely utilized in a stand‐alone microgrid (MG) to regulate power‐sharing among distributed generators (DG). However, over the years, the droop phenomena are continually modified to lessen the deviation in voltage and frequency ...
Sumit Kumar Jha, Deepak Kumar, Prabhat Ranjan Tripathi, Bhargav Appasani, Hossam M. Zawbaa, Salah Kamel   +5 more
doaj   +1 more source

Dynamic Robust Transmission Expansion Planning

, 2016
Recent breakthroughs in Transmission Network Expansion Planning (TNEP) have demonstrated that the use of robust optimization, as opposed to stochastic programming methods, renders the expansion planning problem considering uncertainties computationally ...
García-Bertrand, R., Mínguez, R.
core   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source