Results 91 to 100 of about 765,622 (301)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Adaptive electrothermal protection means for semiconductor converters.

Tekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2017
Thermal management for power converters during normal operation and transient modes when electrical components are warmed up is an actual problem. This can be particularly important for converters with intermittent duty operation, e.g. power supplies for
R. A. Baraniuk, V. A. Todorenko, O. F. Bondarenko   +2 more
doaj   +1 more source

Random Linear Network Coding for 5G Mobile Video Delivery [PDF]

, 2018
An exponential increase in mobile video delivery will continue with the demand for higher resolution, multi-view and large-scale multicast video services.
Delic, Savo, Khirallah, Chadi, Tassi, Andrea, Vukobratovic, Dejan   +3 more
core   +4 more sources

Watchlist Adaptation: Protecting the Innocent

, 2020
One of the most important government applications of face recognition is the watchlist problem, where the goal is to identify a few people enlisted on a watchlist while ignoring the majority of innocent passersby. Since watchlists dynamically change and training times can be expensive, the deployed approaches use pre-trained deep networks only to ...
Günther, Manuel, Dhamija, Akshay Raj, Boult, Terrance E   +2 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Unequal Error Protection Querying Policies for the Noisy 20 Questions Problem

, 2017
In this paper, we propose an open-loop unequal-error-protection querying policy based on superposition coding for the noisy 20 questions problem. In this problem, a player wishes to successively refine an estimate of the value of a continuous random ...
Chung, Hye Won, Hero, Alfred O., Sadler, Brian M., Zheng, Lizhong   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

µPMU-based smart adaptive protection scheme for microgrids

Journal of Modern Power Systems and Clean Energy, 2019
The concepts of microgrids (MGs) and smart grid represent the recent targeted revolution towards fully smart electrical network integrated with high penetration of renewable energy sources (RESs).
Mohamed Salah Elbana, Nabil Abbasy, Ashraf Meghed, Nahil Shaker   +3 more
doaj   +1 more source

Additively Manufactured Dual-Faced Structured Fabric for Shape-Adaptive Protection. [PDF]

Adv Sci (Weinh), 2023
Tian Y, Chen K, Zheng H, Kripalani DR, Zeng Z, Jarlöv A, Chen J, Bai L, Ong A, Du H, Kang G, Fang Q, Zhao L, Qi HJ, Wang Y, Zhou K.   +15 more
europepmc   +1 more source

Reliability-Based Design of Thermal Protection Systems with Support Vector Machines [PDF]

The primary objective of this work was to develop a computationally efficient and accurate approach to reliability analysis of thermal protection systems using support vector machines.
Brune, Andrew J., West, Thomas K., IV, White, Laura M.   +2 more
core   +1 more source