Results 51 to 60 of about 765,622 (301)

Impacts of sea-level rise-induced erosion on the Catalan coast [PDF]

, 2017
The final publication is available at Springer via http://dx.doi.org/10.1007/s10113-016-1052-xThe Catalan coast as most of the developed Mediterranean coastal zone is characterized by the coincidence of stresses and pressures on the natural system with a
Bosom García, Eva, Jiménez Quintana, José Antonio, Nicholls, Robert J., Sánchez-Arcilla Conejo, Agustín, Valdemoro Garcia, Herminia   +4 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Application of Advanced Early Warning Systems with Adaptive Protection [PDF]

, 2015
This project developed and field-tested two methods of Adaptive Protection systems utilizing synchrophasor data. One method detects conditions of system stress that can lead to unintended relay operation, and initiates a supervisory signal to modify ...
Ashrafi, Frank, Babski-Reeves, Kari, Blumstein, Carl, Centeno, Virgilio, Cibulka, Lloyd, King, Roger, Madani, Vahid, Thorp, James   +7 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Adaptive Hybrid Overcurrent Protection Scheme with High Shares of Distributed Energy Resources

Energies
In this research paper, an adaptive and intelligent protection scheme is developed that brings selectivity and sensitivity to the conventional overcurrent relays considering the changes in grid topologies, changes in grid operation modes, and changes in ...
Gourab Banerjee, Christian Hachmann, Jan Lipphardt, Nils Wiese, Martin Braun   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Distributed Coordination Approach for Enhancing Protection System Adaptability in Active Distribution Networks

Energies
The electrical protection of active distribution networks is crucial for ensuring reliable, safe, and flexible operations. However, protecting these networks presents several challenges due to the emergence of bi-directional power flows, network ...
Manuel Acevedo-Iles, David Romero-Quete, Camilo A. Cortes   +2 more
doaj   +1 more source

Spatially explicit groundwater vulnerability assessment to support the implementation of the Water Framework Directive – a practical approach with stakeholders [PDF]

, 2008
The main objective of the study presented in this paper was to develop an evaluation scheme which is suitable for spatially explicit groundwater vulnerability assessment according to the Water Framework Directive (WFD).
Berkhoff, Karin
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Grid Forming Inverter With Increased Short-Circuit Contribution to Address Inverter-Based Microgrid Protection Challenges

IEEE Open Journal of the Industrial Electronics Society
Substantial differences in fault levels between grid-tied and islanded modes is one of the primary challenges of microgrid protection. During grid-tied mode, the bulk grid provides significant short-circuit, while during islanded operation the short ...
Maximiliano Ferrari, Leon M. Tolbert, Emilio C. Piesciorovsky   +2 more
doaj   +1 more source