Results 71 to 80 of about 81,928 (274)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Towards the production of radiotherapy treatment shells on 3D printers using data derived from DICOM CT and MRI: preclinical feasibility studies [PDF]

, 2015
Background: Immobilisation for patients undergoing brain or head and neck radiotherapy is achieved using perspex or thermoplastic devices that require direct moulding to patient anatomy. The mould room visit can be distressing for patients and the shells
C. D. Scrase, D. B. Mortimore, D. Emmens, G. D. Bell, J. Patman, M. D. Tam, M. Hulse, McCloskey, S. C. Short, S. D. Laycock, S. Isherwood, Tam   +11 more
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Salivary Function and Quality of Life Following Adaptive Intensity-Modulated Radiotherapy for Locally Advanced Head and Neck Cancer [PDF]

Research in Oncology
Background: Intensity-modulated radiotherapy (IMRT) is the standard treatment for locally advanced head and neck cancer (LAHNC). However, the potential role of adaptive radiotherapy in preserving salivary function and enhancing quality of life (QoL ...
Wael El-Sheshtawy, Mostafa Mostafa
doaj   +1 more source

Image guidance in radiation therapy for better cure of cancer

Molecular Oncology, 2020
The key goal and main challenge of radiation therapy is the elimination of tumors without any concurring damages of the surrounding healthy tissues and organs.
Vincent Grégoire, Matthias Guckenberger, Karin Haustermans, Jan J. W. Lagendijk, Cynthia Ménard, Richard Pötter, Ben J. Slotman, Kari Tanderup, Daniela Thorwarth, Marcel vanHerk, Daniel Zips   +10 more
doaj   +1 more source

The role of radiotherapy planning images in monitoring malnutrition and predicting prognosis in head and neck cancer patients: a pilot study

Radiation Oncology
Background Adaptive treatment planning can be made in radiotherapy of head and neck cancer patients for reasons such as changes in tumor volume or weight loss.
Beste M. Atasoy, Birsen Demirel, Feyza Nur Ekşi Özdaş, Bennur Devran, Zehra Nur Kılıç, Dilek Gül   +5 more
doaj   +1 more source

Development of a GPU-based Monte Carlo dose calculation code for coupled electron-photon transport

, 2010
Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy.
Amitava Majumdar, Bielajew A F Hirayama H Nelson W R Rogers D W O, Briesmeister J F, Dongju Choi, Gu X, Gu X, Jacques R Taylor R Wong J McNutt T, Josep Sempau, Lensch H Strzodka R, Li J S, Li M, Ma C M, Men C, Nelson W R Hirayama H Rogers D W O, NVIDIA, Salvat F Fernández-Varea J M Baró J Sempau J, Salvat F Fernández-Varea J M Sempau J, Sempau J, Sharp G C, Steve B Jiang, Woodcock E Murphy T Hemmings P Longworth S, Xu F, Xuejun Gu, Xun Jia, Yan G R   +24 more
core   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Study on the Appropriate Timing of Postoperative Adaptive Radiotherapy for High-Grade Glioma

Cancer Management and Research, 2021
Ying Cao,1,* Du Tang,1,* Yining Xiang,1 Li Men,2 Chao Liu,1 Qin Zhou,1 Jun Wu,3 Lei Huo,3 Tao Song,3 Ying Wang,4 Zhanzhan Li,1 Rui Wei,1 Liangfang Shen,1 Zhen Yang,1 Jidong Hong1 1Department of Oncology, Xiangya Hospital, Central South University ...
Cao Y, Tang D, Xiang Y, Men L, Liu C, Zhou Q, Wu J, Huo L, Song T, Wang Y, Li Z, Wei R, Shen L, Yang Z, Hong J   +14 more
doaj