Results 111 to 120 of about 12,788,874 (304)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An Improved Algorithm for Indirect Time domain Analysis of Thin Wire Structures
Journal of Communications Software and Systems, 2012 The algorithm for an indirect time domain (TD) analysis using arbitrary frequency domain method is presented.In previous work, an optimized version of the indirect timedomain method based on adaptive sampling iterative algorithm used in combination with ...
Siniša Antonijević +2 more
doaj
Research on Path Planning Technology of a Line Scanning Measurement Robot Based on the CAD Model
ActuatorsWith the development of robotics and vision measurement technology, the use of robots with line laser scanners for 3D scanning and measurement of parts has become a mainstream trend in the field of industrial inspection.
Huakun Jia +6 more
doaj +1 more source
Temporally adaptive acoustic sampling to maximize detection across a suite of focal wildlife species
Ecology and Evolution, 2019 Acoustic recordings of the environment can produce species presence–absence data for characterizing populations of sound‐producing wildlife over multiple spatial scales.
Cathleen Balantic, Therese Donovan
doaj +1 more source
Improved Adaptive Rejection Metropolis Sampling Algorithms
, 2012 Markov Chain Monte Carlo (MCMC) methods, such as the Metropolis-Hastings (MH) algorithm, are widely used for Bayesian inference. One of the most important issues for any MCMC method is the convergence of the Markov chain, which depends crucially on a ...
Luengo, David +2 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Applied SciencesObjective: Mitochondria drive cellular energy production and regulate key biological processes. High levels of heteroplasmic in mitochondrial DNA (mtDNA) variants can cause mitochondrial dysfunction and clinical symptoms.
Antonina Gospodinova +4 more
doaj +1 more source
How Effectively Can Adaptive Sampling Methods Capture Spontaneous Ligand Binding?
Journal of Chemical Theory and Computation, 2019 Molecular dynamics (MD) simulations that capture the spontaneous binding of drugs and other ligands to their target proteins can reveal a great deal of useful information, but most drug-like ligands bind on time scales longer than those accessible to ...
Robin M. Betz, R. Dror
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source