Results 121 to 130 of about 12,788,874 (304)

Aero-Structural Design Optimization of a Transonic Fan Rotor Using an Adaptive POD-Based Hybrid Surrogate Model

open access: yesAerospace
In this study, an optimization framework for turbomachinery blades using a hybrid surrogate model assisted by proper orthogonal decomposition (POD) is introduced and then applied to the aero-structural multidisciplinary design optimization of a transonic
Jiaqi Luo, Zhen Fu, Jiaxing Li
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Method and apparatus for telemetry adaptive bandwidth compression [PDF]

open access: yes, 1987
Methods and apparatus are provided for automatic and/or manual adaptive bandwidth compression of telemetry. An adaptive sampler samples a video signal from a scanning sensor and generates a sequence of sampled fields.
Graham, Olin L.
core   +1 more source

MAP-Elites for noisy domains by adaptive sampling

open access: yesAnnual Conference on Genetic and Evolutionary Computation, 2019
Quality Diversity algorithms (QD) evolve a set of high-performing phenotypes that each behaves as differently as possible. However, current algorithms are all elitist, which make them unable to cope with stochastic fitness functions and behavior ...
Niels Justesen   +2 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Exploration vs. Data Refinement via Multiple Mobile Sensors

open access: yesEntropy, 2019
We examine the deployment of multiple mobile sensors to explore an unknown region to map regions containing concentration of a physical quantity such as heat, electron density, and so on.
Mohammad Shekaramiz   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Review of Physics-Informed Neural Networks: Challenges in Loss Function Design and Geometric Integration

open access: yesMathematics
Physics-Informed Neural Networks (PINNs) represent a transformative approach to solving partial differential equation (PDE)-based boundary value problems by embedding physical laws into the learning process, addressing challenges such as non-physical ...
Sergiy Plankovskyy   +5 more
doaj   +1 more source

An Adaptive Sampling Algorithm for Target Tracking in Underwater Wireless Sensor Networks

open access: yesIEEE Access, 2018
Target tracking is an important application of underwater wireless sensor networks (UWSNs). Due to the energy constraint and energy imbalanced dissipation of underwater nodes, it is a challenge to maximize the energy efficiency and balance energy ...
Yanlong Sun   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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